Why join us?


LifeMine is a biopharmaceutical company pioneering Top-Down Drug Discovery™, a bold new approach that leverages evolutionary insights from fungi to unearth next-generation precision medicines. Through our data-immersive and technologically expansive discovery engine, we are uniquely positioned to bring mechanistically and structurally novel precision medicines to patients in urgent need of breakthrough disease intervention. LifeMine’s initial pipeline programs are focused in organ transplantation and antifungals. The Company is headquartered in Cambridge, MA, with offices in Gloucester, MA and Basel, Switzerland.


What’s the opportunity?


We are seeking a highly motivated Scientist to join our Discovery and Translational Biology team located in Cambridge, MA. The ideal candidate will have expertise in Immunology, focused on T-cell driven indications. This person should have extensive experience with flow cytometry, primary immune cell readouts and in vivo pharmacology to advance LifeMine’s lifesaving drug Candidates into the clinic to better serve patients.


Job Responsibilities:


  • Propose study designs and conduct experiments to evaluate immunomodulatory response mechanisms in vitro and in vivo.
  • Diligently record, analyze, and present data to team members.
  • Facilitate in vivo pharmacology efforts with key CRO partners.
  • Collaborate across functional teams to efficiently contribute to IND-enabling studies.
  • Contribute to build a robust PK/PD/efficacy relationship and translational biomarker readouts to advance to the clinic.
  • 70% Benchwork

What you’ll need to be successful:


  • PhD in immunology or related field with 3+ years experience in academic, biotechnology or pharmaceutical industry.
  • Extensive experience with primary immune cells whole blood, PBMCs, immune cell subset enrichment and culture/co-culture methods.
  • Proficiency in immunological readouts e.g. MLR, Luminex, MSD, flow cytometry, ELISA.
  • Supporting vivo pharmacology efforts to characterize immunomodulatory efficacy in tissue derived immune cell infiltrates is a plus.
  • Ability to efficiently communicate research questions, propose experiments to deliver key data.
  • Excellent at problem solving and multitasking, with enthusiasm to continually seek avenues to synergize with and support team members.
  • Ability to work independently and thrives in a fast-paced team environment.



Our Culture DNA


Our success at LifeMine is rooted in our unique Culture DNA, shaping how we innovate, collaborate, and achieve our mission. These values drive us forward, pushing the boundaries of science and delivering transformative medicines. 


Collective Genius

We thrive on our ability to think and act as force multipliers for each other, and our collective strength lies in our collaborative spirit and the unique talents of our diverse team. Together, we push the boundaries of science and technology to mine groundbreaking medicines.


Inquisitive Expeditioners

We are pioneers at heart, driven by relentless curiosity to explore uncharted territories in drug discovery, leveraging evolutionary insights from fungi to lead the journey of innovation.


Inspired Learners

We embody a culture of perpetual growth and curiosity, where learning, teaching each other, and innovation intersect. This commitment to exploration and education ensures we remain at the forefront of delivering sophisticated, precision medicines.


Medicine Miners

Mining for high-impact medicines is fundamental to our identity. Through our data-immersive and technologically expansive discovery engine, we bring sophisticated medicines to patients in urgent need. We’re doing more than finding cures; we’re securing a healthier future for humankind.


Apply for this Job

* Required

resume chosen  
(File types: pdf, doc, docx, txt, rtf)
cover_letter chosen  
(File types: pdf, doc, docx, txt, rtf)
When autocomplete results are available use up and down arrows to review
+ Add another education

U.S. Standard Demographic Questions We invite applicants to share their demographic background. If you choose to complete this survey, your responses may be used to identify areas of improvement in our hiring process.
How would you describe your gender identity? (mark all that apply)

How would you describe your racial/ethnic background? (mark all that apply)

How would you describe your sexual orientation? (mark all that apply)

Do you identify as transgender? (Select one)

Do you have a disability or chronic condition (physical, visual, auditory, cognitive, mental, emotional, or other) that substantially limits one or more of your major life activities, including mobility, communication (seeing, hearing, speaking), and learning? (Select one)

Are you a veteran or active member of the United States Armed Forces? (Select one)

Enter the verification code sent to to confirm you are not a robot, then submit your application.

This application was flagged as potential bot traffic. To resubmit your application, turn off any VPNs, clear the browser's cache and cookies, or try another browser. If you still can't submit it, contact our support team through the help center.