Company Summary:  Korro Bio is a privately held biotechnology company focused on the discovery and development of a new class of precision genetic medicines utilizing our propriety RNA editing platform, OPERA. Our portfolio of innovative RNA therapies has the potential to propel genetic medicine beyond rare genetic diseases into larger patient populations with common diseases. Korro enjoys support from a committed group of institutional investors, and recently completed a $116 million Series B financing round to advance our current and future work. We are located in Cambridge, Massachusetts.

We are collaborative and united by a common mission.  We are building a company with extraordinary people with an audacious vision to create transformative genetic medicines for prevalent diseases.  Our values - Rewrite the future, On the Cutting Edge, Better Together, Dynamically Different, Kindness and Integrity form the fabric of the organization.  They are reinforced daily and serve as key dimensions in the hiring process to help us ensure that Korro is a magnet for outstanding talent and a great place to work.

Position Summary:  We are seeking a highly motivated Associate Scientist to join our Platform Cell Biology Team.  This lab-based position will focus on driving our understanding of ADAR RNA editing biology through a variety of cellular, molecular, and biochemical based assays.  The candidate will be responsible for the design and execution of assays, including data analysis and interpretation.  The candidate should have demonstrated proficiency in a variety of cell-based assays including routine handling of mammalian cell cultures (passaging, freezing, transfection, etc…).  Experience with RT-qPCR, Western Blotting, immunofluorescence and/or biochemical assays preferred.  The candidate will be a motivated team player, have excellent interpersonal and communication skills as well as be able to balance multiple high-priority tasks.

Key Responsibilities: 

  • Design, execute and troubleshoot various cell-based assays to further the company’s understanding of ADAR based RNA Editing including, but not limited to, RNA isolation, PCR, qPCR, NGS, digital PCR, Western Blotting, and immunofluorescence.
  • Document, analyze and interpret data, proposing next steps.
  • Effectively communicate and present data to the broader team, working collaboratively to align on the best path forward.
  • Continually evaluate relevant literature, participate in journal club meetings as well as continually evaluate landscape for new assays or techniques to improve workflows and/or results.
  • Contribute effectively to projects in a multi-disciplinary team environment.

Required Qualifications:

  • MS with 1-2+ or BS with 5-8+ years of experience in molecular and/or cell biology, or related field.
  • Broad experience in the application of cell-based and molecular biology or biochemical-based techniques such as mammalian cell culture, RNA isolation, PCR, qPCR, NGS, Western blotting and immunofluorescence.
  • Experience with cell-based high-throughput assays in a 96-well format.
  • The ability to learn and implement new techniques and adapt rapidly is essential.
  • Excellent attention to detail, time management, and documentation.
  • The candidate must be able to analyze, report and communicate data rigorously.
  • Ability to multitask and successfully interact with a diverse team of scientists to deliver quality data and results.

Other Knowledge, Experience or Skills recommended

  • Experience with confocal microscopy is a plus.
  • Experience with biochemical assays or protein purification is a plus.

Candidates who are keen experimentalists, independent thinkers, and enthusiastic team players that have a passion for drug discovery are encouraged to apply.

Benefits:  Korro offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance, a dependent care flexible spending account and a Company-funded health savings account and free parking.

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