What if… you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies to transform health care?
In today’s healthcare system, disease diagnosis often relies on invasive procedures, such as biopsies, which enable direct interrogation of cellular and tissue health at the suspected source of disease. Due to their invasiveness, cost, and general inconvenience to the patient, biopsies are often conducted after onset of symptomatic disease presenting one of the largest barriers to delivering interventions early in disease progression when they are likely to be most impactful. Flagship Labs 103, Inc. is a privately held early-stage company that is building advanced technological and computational platforms to pioneer the detection of cellular dynamics from minimally invasive biospecimens that can be leveraged to connect individuals to the most effective interventions to prevent onset and progression of disease.
FL103 was founded by Flagship Pioneering, an innovation enterprise dedicated to originating and developing companies that invent breakthrough technologies that transform health care, agriculture, and sustainability. Since Flagship’s founding in 2000, the firm has originated and fostered more than 100 scientific ventures including Moderna Therapeutics, Generate Biomedicines, and Indigo Agriculture.
Position Summary:
FL103 is seeking a highly motivated and experienced computational biologist to join our early-stage biotech company. The successful candidate will be a driven, experienced scientist who is enthusiastic about developing state-of-the-art techniques to pioneer the detection of cellular dynamics from minimally invasive biospecimens. The position will provide a unique opportunity to play a foundational role in the development of FL103’s innovative bioplatform.
Responsibilities:
- Establish computational approaches to interrogating and contextualizing signals from extracellular vesicles isolated from human biospecimens
- Conduct multi-omic analyses of human biospecimens and derivative datasets
- Collect, review, and leverage public data to dissect early disease transitions from minimally invasive biospecimens
- Support design and analysis of data from cellular biology experiments to support key hypotheses
- Maintain scientific and technical expertise through familiarity with scientific literature
- Coordinate with Contract Research Organizations (CROs) and external collaborators
- Communicate experimental results effectively through oral presentations and written reports, ensuring clear and concise dissemination of information to the FL103 team
- Help lead, mentor, and build a computational team
Qualifications:
- PhD in computational biology, systems biology, bioinformatics, computer science or related fields with 2-4 years of industry / postdoctoral experience
- Experienced in standard and advanced computational support of wet-lab experimental design (e.g. power analysis, Bayesian experiment planning)
- Hands-on experience with a modern machine learning framework like PyTorch or TensorFlow (required)
- Understanding of NGS approaches and demonstrated ability to collaborate with experimental biologists
- Experience analyzing -omics data (e.g., single-cell and bulk RNA-seq, proteomics) using a scientific programming language such as R or Python
- Experience with both statistical inference and machine learning (e.g random forests, SVMs, neural networks, transformers, etc.)
- Ability to manage multiple projects, working both independently and collaboratively within a dynamic team
- Excellent written and verbal communication skills to present results and scientific data to the internal team and/or collaborators
- Highly attentive to detail, flexible, and curious
- Enthusiastic about playing a pivotal role in building the foundation of a new biotech company
About Flagship
Flagship Pioneering is a biotechnology company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.
Flagship Pioneering is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.
Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.