Company Summary

What if…you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability?

Apriori Bio is an early-stage biotechnology company with an ambitious and exciting mission: to lay the foundation for Global Pathogen Shield™ protective interventions that that can neutralize a wide range of the most dangerous and rapidly evolving infectious pathogen threats.  The company is developing a revolutionary approach to this challenge and recruiting a team of top-tier scientists to build what it believes will be a powerful, first-in-category R&D platform.

Flagship Pioneering is a biotechnology company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at

The Role:

We are seeking a highly skilled and experienced Principal Immunologist to join our team and lead our efforts in vaccine and adjuvant development. You will play a critical role in designing, developing, and evaluating novel vaccines and adjuvants to combat infectious diseases and enhance immune responses. You will collaborate with a multidisciplinary team of scientists and researchers to drive innovation and contribute to the advancement of vaccine development.


  • Support and facilitate the design, development, and evaluation of vaccine candidates
  • Engage in the active development, optimization, and implementation of immunoassays for vaccine antigens
  • Design and execute experiments to evaluate the immunogenicity, efficacy, and safety of vaccine candidates and immune enhancers using appropriate in vitro and in vivo models
  • Analyze and interpret experimental data, and present findings to internal stakeholders and external scientific communities
  • Collaborate with cross-functional teams to optimize vaccine and adjuvant formulations
  • Effectively handle multiple projects and deliverables, including evaluating workload, prioritizing tasks, and determining resource needs to achieve the objectives of the core or project teams
  • Provide scientific expertise and guidance to junior scientists and research associates, fostering a collaborative and innovative work environment
  • Conduct in-depth literature reviews and stay up-to-date with the latest advancements in immunology, vaccine technologies, and adjuvant formulations
  • Stay informed about regulatory guidelines and ensure compliance with relevant regulations and standards in vaccine and adjuvant development


  • Ph.D. in Immunology, Virology, Microbiology, or a related field with 12+ years post-PhD experience (at least 5 years in industry)
  • Research experience in vaccines (especially influenza and/or SARS-CoV-2) or in the development of adjuvant systems or immune enhancing molecules is highly desirable
  • Strong expertise in immunological techniques and assay design/ development, including flow cytometry, ELISA, electrochemiluminescent (ECL) assays, cell-based assays such as ELISPOT and/or ASC assays, and animal models
  • Proficient in problem-solving and critical thinking, with a demonstrated ability to work both independently and collaboratively within a matrixed organizational structure
  • Adaptable in navigating a dynamic and constantly-changing research landscape
  • Extensive knowledge of vaccine technologies, adjuvant formulations, and immune response mechanisms
  • Experience in designing and conducting preclinical and/or clinical studies, including protocol development, data analysis, and interpretation
  • Proficient in data analysis software and statistical tools
  • Excellent communication and presentation skills, with the ability to effectively communicate complex scientific concepts to both technical and non-technical audiences
  • Strong leadership skills and the ability to work collaboratively in a multidisciplinary team environment
  • Prior experience in mentoring and supervising junior scientists is preferred
  • Knowledge of vaccine regulatory landscape and experience interacting with regulatory agencies is a plus

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

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