Company Summary

Cellarity's mission is to bring breakthrough medicines to patients by completely redefining the way drugs are discovered. Founded by Flagship Pioneering in 2017, Cellarity is designing medicines against the cell as opposed to a single molecular target. The company has developed a unique combination of expertise across network biology, high-resolution data, and machine learning to unlock new treatment options in a vast array of disease areas. Cellarity currently has drug discovery programs underway in metabolic disease, hematology, immuno-oncology and respiratory disease. The company has raised $123 million as part of a Series B funding round with contributions from world renown investors such as Blackrock, The Baupost Group, Banque Pictet, alongside Flagship Pioneering.

What if you could join a rapidly growing company and play a critical role in bringing new medicines to patients through looking at and treating disease in a revolutionary way.

Founded by Flagship Pioneering, Cellarity is the first company developing medicines through an understanding of cell behaviors. The company’s broad platform harnesses single-cell technologies and machine learning to digitize and quantify cellular behaviors, unravel the network dynamics that govern those behaviors, and generate medicines that can direct them. Cellarity is using its platform to design medicines targeting the full cellular and molecular complexity of disease, enabling a quantum leap in the success rate and speed of drug discovery, design and development. For additional information, visit


Position Summary:

Cellarity is seeking a highly motivated and innovative Director/Senior Director with expertise in the field of medicinal chemistry to play a vital role in the company’s efforts to validate novel discovery approaches based on cell behavior.

The candidate will be reporting to the Head of Medicinal Chemistry and would be expected to utilize Cellarity’s AI-augmented novel drug discovery paradigm, to lead, motivate and develop a team of medicinal chemists (internal and external) through early hit discovery, lead optimization, drug candidate identification and IND enabling assessment. The successful candidate will have deep experience in small molecule drug discovery and will drive the application of cutting-edge molecular, computational, and AI-augmented design approaches to discover quality drug candidates that can become transformative medicines for serious diseases.

They will be comfortable working in and contributing to a very dynamic and cross-functional team environment. The ideal candidate must be independent, results oriented, with excellent communication skills and be willing to work in a highly dynamic and fast-paced entrepreneurial environment.


Key Responsibilities:

  • Provide creative and innovative leadership of Medicinal Chemistry enabling the Company to convert strong biological hypotheses into transformative medicines
  • Ensure effective interaction & communication between medicinal chemistry, computational chemistry, machine learning, computational biology, and drug discovery teams  
  • Lead the department to ensure that it operates at the highest levels of scientific excellence
  • Manage project resourcing for the Medicinal Chemistry group
  • Lead and/or contribute to cross-functional goals within Cellarity
  • Work closely with Head of chemistry and CROs to ensure that the medicinal chemistry group employs the highest standards and most advanced methodologies in drug discovery
  • Develop and manage Cellarity’s small molecule IP portfolio. Work closely with attorneys to plan, create, and execute an aggressive IP strategy to protect and expand Cellarity’s intellectual property



  • PhD in Organic/Medicinal Chemistry with 15+ years of industry experience in medicinal chemistry leadership roles such that a clear track record of success in Drug Discovery can be readily demonstrated
  • An extensive track record of presentations, publications, and patents
  •  A high degree of self-motivation, organization, communication, and presentation skills; high competence in solving complex problems, as well as the ability to navigate a fast-paced cross-functional and collaborative work environment
  • Demonstrated ability for people leadership and talent development
  • A desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases
  • Strengths in the following areas: creativity, problem-solving, and managing relationships within a matrix project team environment (internal/external partners)
  • Demonstrated ability to successfully work in cross-functional teams with an emphasis on teamwork, collaboration, and communication
  • Self-driven and demonstrated ability in working with a diverse team in a fast-entrepreneurial setting
  • Experience with utilizing computational chemistry tools and structure-based drug design principles for lead identification and optimization
  • Ability to collaborate with and manage internal experts and external consultants.
  • Drug discovery experience in multiple therapeutic areas and target classes
  • Experience in leading projects and driving programs from initiation through lead optimization phase to clinical lead selection.
  • Demonstrated synthetic and medicinal chemistry skills through high quality publications/patents
  • Excellent communication skills.
  • Strengths in the following areas: creativity, problem-solving, and managing relationships within a matrix project team environment (internal/external partners).
  • Demonstrated ability to successfully work in cross-functional teams with an emphasis on teamwork, collaboration, and communication within team and across the department



Cellarity is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Recruitment & Staffing Agencies: Cellarity does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Cellarity or its employees is strictly prohibited unless contacted directly by Cellarity’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Cellarity, and Cellarity will not owe any referral or other fees with respect thereto.

Apply for this Job

* Required
+ Add Another Employment