Company Summary:

Laronde is pioneering a platform that offers a novel way of modulating human biology. Endless RNA™ (eRNA) is a uniquely engineered RNA that can be programmed to express diverse proteins inside the body. It is long lasting, non-immunogenic, allows for repeat dosing, and offers flexibility in formulation and delivery.

Laronde was founded in 2017 by Flagship Labs, the innovation foundry of Flagship Pioneering. Laronde has raised a record breaking $440 Million in a Series B Financing to advance the development of its eRNA platform. There is a broad pipeline of programs across therapeutic categories with the goal of 100 medicines in 10 years. To learn more, please visit the company’s website at https://www.laronde.bio/about.

Position Summary:

Laronde is seeking an outstanding Bioinformatics Scientist at the Scientist or Senior Scientist level to join a multidisciplinary team of experimental and computational synthetic biologists and engineers responsible for study, design and optimization of novel endless RNA (eRNA) therapeutics. The ideal candidate will have experience in analysis, interpretation and method development of diverse Next Generation Sequencing (NGS) data, especially pertaining to analysis of RNA, and a high degree of proficiency in Python and experience in collaborative software development including git version control and test-driven development. The candidate will work as part of a team of bioinformaticians and will develop bioinformatics tools and pipelines to support both custom and standard NGS data analysis. If you are passionate about your work and want to contribute to the cutting-edge RNA therapeutics, we are looking for you.

This role will be based at our 101 South Street Sommerville, MA site. There is flexibility to work from home 1-2 days per week.


Key Responsibilities:

  • Develop and implement robust customized data processing pipelines for various NGS data including single-cell RNA-seq, ribosome profiling, and SHAPE-MaP.
  • Perform custom analysis and report generation of large, complex datasets from a variety of experimental assays.
  • Write documentations and tests for the bioinformatics tools and pipelines developed.
  • Work closely with the lead bioinformatician and other scientists
  • Maintain scientific and technical expertise through familiarity with scientific literature
  • Work within an entrepreneurial, highly-collaborative, interdisciplinary, and fast-paced environment

Qualifications:

  • PHD in bioinformatics, computational biology or genomics with expertise in RNA biology
  • At least 2+ years of post-doctoral experience in academia or industry with a broad range of current bioinformatics and computational biology tools, methods, and applications
  • Knowledge of molecular biology, especially as related to translatable RNA
  • Excellent analytical and programming skills
  • Knowledge and experience of best-practice software development, including version control, unit and integration testing, documentation, and deployment
  • GitHub repositories and publications that can showcase your skills
  • Excellent communication and time management skills
Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
 
Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

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