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4DMT is a leading late-stage biotechnology company advancing durable and disease-targeted therapeutics with potential to transform treatment paradigms and provide unprecedented benefits to patients. The Company’s lead product candidate 4D-150 is designed to be a backbone therapy forming the foundation of treatment of blinding retinal vascular diseases by providing multi-year sustained delivery of anti-VEGF (aflibercept and anti-VEGF-C) with a single, safe, intravitreal injection, which substantially reduces the treatment burden associated with current bolus injections. The Company’s lead indication for 4D-150 is wet age-related macular degeneration, which is currently in Phase 3 development, and second indication is diabetic macular edema. The Company’s second product candidate is 4D-710, which is the first known genetic medicine to demonstrate successful delivery and expression of the CFTR transgene in the lungs of people with cystic fibrosis after aerosol delivery

GENERAL SUMMARY:

In this position, you’ll work closely with HR leadership and the team to ensure HR operations run smoothly, compliantly, and with a focus on continuous improvement. The Manager, HR Operations & Systems will own core HR processes and compliance requirements while also playing a major role in the execution of key HR programs, including performance management, talent acquisition, learning & development, and employee engagement. This role is responsible for maintaining accurate employee data, stewarding HR systems, driving automation and efficiencies, and delivering analytics that provide insights into workforce trends. This role helps ensure both the HR team and the broader organization are set up for success.

MAJOR DUTIES & RESPONSIBILITIES:

HR OPERATIONS:

Own and continuously improve HR operations processes (onboarding, offboarding, employee changes, documentation, records management).
Maintain and update SOPs to ensure compliance and effectiveness.
Partner with Finance, IT, and Payroll to ensure timely and accurate processing of employee data and changes.
Serve as point of contact for HR service requests, escalating as needed.
Regularly evaluate HR operations to identify opportunities for simplification, standardization, and improved employee experience.

HR COMPLIANCE:

Own compliance activities across HR, including policy administration, record retention, and regulatory reporting.
Ensure HR processes and documentation meet requirements of SOX, D&I, federal/state laws, and other regulations applicable to a publicly traded company.
Conduct audits of employee files, HR data, and HR processes to ensure accuracy and compliance.
Partner with Finance, IT, and external vendors on compliance-related audits.
Monitor and integrate new regulations and best practices into HR policies, processes, and the employee handbook.

HR TECHNOLOGY:

Administer current HR systems, including user access, permissions, and documentation.
Ensure HR data accuracy, integrity, and compliance with SOX controls, data privacy, and record retention requirements.
Partner with IT and vendors to maintain existing tools, evaluate effectiveness, and make incremental improvements where needed.
Provide user support and training for HR systems to ensure adoption and consistency.
Drive automation and process efficiencies within HR operations
Identify areas of improvement with current HR systems to optimize utilization and efficiency through enhancements and integration of different tools.
Explore and evaluate AI-powered HR technologies to automate tasks and improve data analysis, collaborating with IT and HR partners to pilot solutions, monitor effectiveness, and recommend scalable integration.

HR PROGRAMS & ANALYTICS:

Lead the operational and systems aspects of HR programs throughout the year, including performance management, talent acquisition processes, learning & development, and employee engagement initiatives.
Partner with HR leadership and program owners to coordinate timelines, communications, and execution steps to ensure successful delivery.
Train HR team members and employees on how to navigate and use HR systems and resources effectively.
Maintain accurate program documentation and monitor utilization to evaluate effectiveness.
Develop and deliver HR analytics and reporting that provide insights into workforce trends, headcount, and program outcomes to inform decision-making.
Continuously evaluate HR programs and processes to identify opportunities for improvement and alignment with organizational goals.

QUALIFICATIONS:

Education:

Bachelors required

Experience:

6+ years of progressive HR experience, with strong emphasis on HR operations, systems, and compliance.
3+ years of experience managing HR Operations is preferred.
Experience supporting Sox compliance for a publicly traded company.
Experience with one or more of the following tools a plus: Greenhouse Recruiting, ChartHop, Leapsome, Nectar.

Other Qualifications/Skills:

Hands-on experience with ADP Workforce Now (maintenance, data integrity, user support).
Strong knowledge of HR compliance requirements, record retention, and reporting.
Demonstrated ability to manage and improve HR operations processes.
Proficiency in Excel, PowerPoint, and HR reporting.
Highly organized with strong attention to detail and documentation skills.
Excellent written and verbal communication; able to partner effectively across teams.
Customer-service orientation with ability to balance employee experience and compliance requirements.

Travel: 0-10%

Physical Requirements and Working Conditions:

Physical Activity - Repetitive motions: Making substantial movements (motions) of the wrists, hands, and/or fingers. Fingering: Picking, pinching, typing or otherwise working, primarily with fingers rather than with whole hand or arm as in handling. Talking: Expressing or exchanging ideas by means of the spoken word.
Physical Requirements - Sedentary work: Exerting up to 10 pounds of force occasionally and/or a negligible amount of force frequently or constantly to lift, carry, push, pull or otherwise move objects, including the human body. Sedentary work involves sitting most of the time. Jobs are sedentary if walking and standing are required only occasionally, and all other sedentary criteria are met.
Working Conditions - The worker is not substantially exposed to adverse environmental conditions (as in typical office or administrative work).

Base salary compensation range: $135,000/yr - $165,000/yr

4DMT provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, gender, sexual orientation, national origin, age, disability, genetic information, marital status, status as a covered veteran, and any other category protected under applicable federal, state, provincial and local laws.

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