Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers.  The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

The Senior Director, Global Medical Strategy, Pancreatic Ductal Adenocarcinoma (PDAC) and Colorectal Cancer (CRC) is a key member of the Medical Affairs team. Reporting to the Executive Director and Head of Medical Strategy for Gastrointestinal Cancers, this individual will be responsible for developing and executing the Global Medical Affairs (GMA) strategy and tactical plans with a focus on launch readiness and life cycle management for medicines across PDAC and CRC indications. The successful candidate will have a proven track record of developing and driving medical strategy for multiple assets with a focus on effectively communicating key scientific data through publications, medical information, medical communications, congress activities as well as gathering insights through Advisory Boards and Key Opinion Leader (KOL) engagements. He/she must work collaboratively with cross-functional counterparts in Development, Research and Commercial as well as other partners in the organization to design and implement a medical strategy for PDAC indications.

Key aspects of the role include the following: support the development and execution of the multi-year global and US medical strategy for PDAC and CRC, including oversight of the publication and medical communications strategy, integrated evidence planning, lifecycle management and budget planning process. He/she will also be expected to support the GI Global Medical Affairs Team (GMAT) to execute medical strategies, contribute to the operations and oversight of medical activities associated with PDAC and CRC, work cross-functionally to support associated pre-launch activities, provide regular updates and support to senior leadership.

The ideal candidate is a skilled and collaborative leader, highly effective communicator, entrepreneurial, detail-oriented, proactive, and scientifically driven.

  • Serves as a member of the Global Medical Affairs Team contributing to overall medical portfolio management and prioritization as well as contributing to the development of the multi-year GMA strategic plan.

  • Supports development and execution of the GMA PDAC and CRC strategy and medical objectives including activities related to scientific engagement and communication, evidence generation, internal education, and patient advocacy.

  • Leads integrated evidence generation planning in PDAC and CRC including conducting routine cross-functional gap assessments leading to the development/refinement of a publication strategy, an evidence generation plan, and tactical plan as part of the overall GMA plan.

  • Provides medical leadership in scientific engagement activities with key external stakeholders through organizing and leading PDAC and CRC advisory boards, study investigator interactions, congress activities, and peer-to-peer discussions with the goal of communicating scientific insights to internal teams to drive strategy.

  • Serves as a senior medical leader communicating clinical and scientific data to physicians and other healthcare professionals through presentations, educational programs, and scientific discussions.

  • Supports medical contribution to cross-functional strategy team meetings including Clinical and Safety sub-teams, product team, Market Access, commercial and other cross-functional strategic discussions.

  • Works closely with the Clinical and MSL teams to provide enrollment, scientific, and engagement support to ensure clinical trials meet study timelines.

  • Partners with RWE strategy and translational teams on related integrated evidence generation strategies and activities as part of the GMA Plan.

  • Partners with Patient Advocacy to incorporate the patient voice and define external medical education strategies for independent grants, respectively.

  • Support competitive intelligence team activities through landscape assessments, development of patient journey, and congress insights

  • Provides medical support for scientific symposia and medical congresses and collaborate across GMA functions to develop, review, and align on key scientific communication points and medical information response documents within legal and compliance guidelines.

  • Supports the review and approval of abstracts, manuscripts, corporate communications, and other documents as well as internal stakeholder medical education activities related to the compound data and related competitor data.

  • Provides medical strategy leadership for expanded access programs (EAP) and investigator sponsored research (ISR) for PDAC and CRC.

  • Manages budgets and resources efficiently for GMA supported activities in PDAC and CRC to maximize RevMed resources.

  • Adheres to Revolution Medicines Core Values and policies. 

Required Education, Experience, and Skills:

  • An advanced doctorate degree (PharmD, PhD, MD, DO or equivalent) in medical/scientific area is required. 

  • Ten years minimum experience in academic medicine, biotech and/or pharmaceutical industry, with at least five years of experience in oncology research and/or patient care.

  • Must have a strong scientific background in oncology with good understanding of biomarker-driven disease and ability to effectively analyze, synthesize, and communicate complex scientific information.

  • Strong networking skills with deep existing relationships with oncology healthcare professionals including global top key opinion leaders required.

  • Experience in KOL mapping and development of engagement plans required.

  • Previous overall responsibility and accountability for medical affairs activities, including budget management for more than one compound (pipeline and marketed).

  • Direct, hands-on experience executing the activities of various functions within medical affairs (training, medical communications, medical information, EAP, Evidence Generation, publications).

  • Extensive experience in global product launches including support of integrated brand plan ideation, regulatory submissions, reimbursement, and label development.

  • Proven track record of clinical trial support including protocol development/review, site selection support, enrollment support, and data analysis.

  • Experience conducting gap assessments and executing evidence generation plans including the developing and running of medical affairs company sponsored studies (MACS), ISRs, and Health Economics and Outcomes Research (HEOR) projects.

  • Excellent verbal, written, and presentation skills with the ability to effectively communicate complex scientific data to diverse audiences.

  • Thrives in fast-paced, dynamic environment and can manage multiple priorities at one time with little direction.

  • Ability to travel to Redwood City headquarters and professional congresses (30-40%).

  • Manage and adhere to RevMed policies, ensuring compliance with corporate rules and government regulations.

  • Commitment to RevMed Core Values. 

Preferred Skills:

  • Experience in guideline submissions (e.g. NCCN) and engagements with global health authorities preferred.

The base salary range for this full-time position is $236,000 to $295,000 for candidates working onsite at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the salary for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.

Please note that base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com.

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