ElevateBio is a cell and gene therapy technology company built to power the development of transformative cell and gene therapies today and for many decades to come. The company has assembled industry-leading talent, built world-class facilities, and integrated diverse technology platforms necessary for rapid innovation and commercialization of cell, gene, and regenerative therapies.

The Role:

We are seeking a motivated and creative Associate Scientist to join our team to support generation and characterization of CAR and TCR T cells. Reporting to the Senior Scientist, Cell Therapy Discovery, the successful candidate will drive engineering and characterization of T cells for allogeneic/universal T cell approaches. The individual will contribute to a variety of cell therapy programs in multidisciplinary manner. Their efforts will be crucial to accelerating our cutting-edge cell therapy programs.

Here’s What You’ll Do:

  • The individual will work in the laboratory and be responsible for the experimental execution and data analysis for research studies supporting cutting edge therapeutic programs and platform discovery research.
  • Employ viral vector strategies for the genetic modification of human T cells.
  • Develop and conduct in vitro analytical and functional bioassays for characterizing CAR and TCR engineered T cells including expression, efficacy, and cytokine production.
  • Assist in the expansion and cell banking of engineered cell lines, laboratory maintenance, generation of protocols and other technical documents as needed.

Requirements:

  • Bachelor or Master of Science (MS preferred) in Immunology, Biology, Molecular Biology or Biochemistry, with 5+ years of hands-on experience in the development of new biological therapeutics or pharmaceutical products is required
  • Direct experience with flow cytometry, primary human T cell culture and techniques to characterize primary T cells including cytokine analysis, cytotoxicity, and proliferation assays is required
  • Experience working with a variety of human immune cells (PBMC, NK, macrophages) is preferred.
  • Experience in lentiviral infection of T cells, molecular biology, cloning, and protein chemistry (PAGE, Western blot, ELISA), as well is preferred.
  • Detail-oriented, organized, and technically skilled.
  • Highly adaptable and responsive, and committed to completing tasks in a timely fashion.
  • Demonstrated ability to work in a dynamic environment as a team player with a strong work ethic.
  • Excellent team player with good interpersonal and communication skills.
  • Able to maintain written records in the form of laboratory notebooks (paper or electronic).
  • Excellent oral and written communication skills.

 

Why join ElevateBio?

ElevateBio is accelerating the future of biotechnology; developing the next-generation of cell, viral and regenerative medicine therapeutics for the treatment of severe diseases.  We have launched a revolutionary new model that integrates innovators, infrastructure and capital to effectively develop cell, gene and related therapies for patients with severe and life-threatening disorders.  With plans for a cutting-edge laboratory and manufacturing center already underway, we're building a world-class organization lead by expert talent with bench-to-bedside capabilities.

At the heart of the ElevateBio platform is ElevateBio Base Camp, a state-of-the-art research, development and manufacturing center for innovation in the Greater Boston Area to be staffed with a world-class team of scientists.

Our Vision:
Next-generation product development for advanced therapies supported by global bench-to-bedside expertise shared across our portfolio of companies

ElevateBio is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. ElevateBio will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

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