At Element Biosciences, we are passionate about our mission to develop high performing products to study genomics with unprecedented flexibility and quality that enable researchers to better understand biology for the improvement of global health. We have built a highly efficient product-driven organization where employees can learn, grow, and thrive in a challenging but encouraging environment. We are committed to scientific integrity, collegiality, honesty, objectivity, and openness.

We are seeking a Staff Optomechanical Engineer to drive optomechanical design of complex scientific instruments integrating optics, fluidics, motion, thermal, and electrical functions. This is a key role within our instrument mechanical engineering group requiring a technical expert with previous experience collaborating closely with cross-functional teammates from R&D and Operations. Strong engineering fundamentals, rigorous critical thinking skills, and a methodical product development approach are essential attributes to being successful in the role. This position will be on-site at our San Diego headquarters.

If you possess the following and want to make a meaningful impact, we invite you to explore this role.

Essential Functions and Responsibilities:

  • Drive the design, prototyping, and commercialization of new optomechanical solutions in close collaboration with the optical system design team.
  • Design mechanical structures to interface with and integrate the optical system into advanced desktop scientific instruments.
  • Manage internal and external optomechanical development projects.
  • Contribute to interdisciplinary root cause analysis involving structural tolerance loops, material and thermal sources of variation, and other optical considerations.
  • Translate market requirements into optomechanical architecture, product requirements, module designs, and component selection.
  • Develop test protocols, metrology tools and methods, and calibration/adjustment approaches to achieve optical performance targets.
  • Verify and transfer reliable optomechanical designs from R&D to Operations. Support existing product line and cross-functional troubleshooting as required.
  • Lead design reviews, sourcing and procurement, and integration of proof of concept and prototype optomechanical assemblies.
  • Contribute to the company’s product development roadmap by exploring new technologies and design concepts.
  • Other duties, as assigned.

Education and Experience:

  • BS required (MS preferred) in Mechanical Engineering and 8+ years of relevant work experience (or equivalent combination of education and industry experience).
  • Proven track record as a lead optomechanical engineer on development programs spanning from concept to commercialization.
  • Solid understanding of the fundamentals of optomechanical design including kinematic mounts, exact constraint, tolerance analysis, material selection, and thermally stable design.
  • Expertise and proficiency with SolidWorks required. Familiarity with SolidWorks FEA packages a plus.
  • Experience with component and assembly metrology methods required.
  • Familiarity with Structural-Thermal-Optical-Performance (STOP) analysis a plus.
  • Excellent first-principles-focused mechanical engineer with insight into optomechanical design challenges.
  • Proactive self-starter who drives action, investigations, and delivers results without task-level structured guidance.
  • Demonstrated ability to navigate uncertainty in a fast-paced, interdisciplinary environment and quickly adjust to evolving technology and priorities.
  • Excellent written and verbal communication skills, capable of clearly explaining technical issues and ideas to peers and management.


  • Must be able to lift 15 pounds


  • San Diego


  • N/A

Job Type:

  • Full Time, Exempt

Base Compensation Pay Range: 

  • $125,800 - $165,267

In addition to base compensation noted above, you will be eligible for stock options, discretionary annual bonus, no cost health insurance plans, 401k with company match, and flexible paid time off. 

Please note: Base compensation will depend on multiple factors, including geographic location, qualifications, and experience. 

We foster an environment such that all people are afforded the freedom to pursue their passions without regard to race, color, religion, national or ethnic origin, gender (including pregnancy), sexual orientation, gender identity or expression, age, disability, veteran status or any other characteristics protected by law.

Apply for this Job

* Required

resume chosen  
(File types: pdf, doc, docx, txt, rtf)
cover_letter chosen  
(File types: pdf, doc, docx, txt, rtf)

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file.

As set forth in Element Biosciences’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law.

Race & Ethnicity Definitions

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measure the effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categories is as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.

Voluntary Self-Identification of Disability

Form CC-305
Page 1 of 1
OMB Control Number 1250-0005
Expires 04/30/2026

Why are you being asked to complete this form?

We are a federal contractor or subcontractor. The law requires us to provide equal employment opportunity to qualified people with disabilities. We have a goal of having at least 7% of our workers as people with disabilities. The law says we must measure our progress towards this goal. To do this, we must ask applicants and employees if they have a disability or have ever had one. People can become disabled, so we need to ask this question at least every five years.

Completing this form is voluntary, and we hope that you will choose to do so. Your answer is confidential. No one who makes hiring decisions will see it. Your decision to complete the form and your answer will not harm you in any way. If you want to learn more about the law or this form, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website at

How do you know if you have a disability?

A disability is a condition that substantially limits one or more of your “major life activities.” If you have or have ever had such a condition, you are a person with a disability. Disabilities include, but are not limited to:

  • Alcohol or other substance use disorder (not currently using drugs illegally)
  • Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, HIV/AIDS
  • Blind or low vision
  • Cancer (past or present)
  • Cardiovascular or heart disease
  • Celiac disease
  • Cerebral palsy
  • Deaf or serious difficulty hearing
  • Diabetes
  • Disfigurement, for example, disfigurement caused by burns, wounds, accidents, or congenital disorders
  • Epilepsy or other seizure disorder
  • Gastrointestinal disorders, for example, Crohn's Disease, irritable bowel syndrome
  • Intellectual or developmental disability
  • Mental health conditions, for example, depression, bipolar disorder, anxiety disorder, schizophrenia, PTSD
  • Missing limbs or partially missing limbs
  • Mobility impairment, benefiting from the use of a wheelchair, scooter, walker, leg brace(s) and/or other supports
  • Nervous system condition, for example, migraine headaches, Parkinson’s disease, multiple sclerosis (MS)
  • Neurodivergence, for example, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, dyslexia, dyspraxia, other learning disabilities
  • Partial or complete paralysis (any cause)
  • Pulmonary or respiratory conditions, for example, tuberculosis, asthma, emphysema
  • Short stature (dwarfism)
  • Traumatic brain injury

PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.

Please reach out to our support team via our help center.
Please complete the reCAPTCHA above.