Denali Therapeutics is dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine.  Our rigorous, data-driven approach to science is supported by strategic business principles that include a broad portfolio of diverse therapeutic modalities, parallel investments, and leveraging global collaborations.


The Opportunity:

The Patent Counsel will work closely with our dynamic and growing Legal team and help build and defend Denali’s IP portfolio.  

Since our founding in 2015, we have built a diverse pipeline including 7 clinical-stage programs, and we need your help to achieve our goal of defeating degeneration.  Between our Transport Vehicle (TV) platform for delivering drugs to the brain, our diverse clinical and pre-clinical portfolio, and the many collaborations we leverage, there are many rewarding opportunities for a patent attorney to make a significant impact by protecting our inventions and ultimately helping patients suffering from these terrible diseases.  

Reports to the Vice President of Intellectual Property & Transactions.



  • Creatively draft, file, and prosecute patent applications that protect Denali inventions and create lasting business value
  • Partner with scientists and team leaders to understand the direction of early-stage neuroscience research and participate in experimental planning to generate data to support the IP strategy
  • Develop and implement thoughtful and creative prosecution strategies for U.S. and foreign patent portfolios to build a strong yet cost-effective global IP position
  • Conduct patentability and freedom-to-operate searches, and analyze third party patent estates to identify risks and opportunities; communicate business-oriented advice regarding the results to Denali Leadership and project teams, including design solutions and risk mitigation strategies
  • Partner with outside counsel to foster long-term relationships, and manage the relationships by prioritizing and focusing the work done externally, so that Denali achieves cost-effective, high quality legal results
  • Support global research and development collaborations by assisting the Contracts team in reviewing, drafting, negotiating, and implementing agreements, and by assisting the Corporate Development team by supporting the business with new and existing collaboration agreements
  • Contribute to the growing Legal team by identifying creative ways for the team to improve and develop new capabilities in order to achieve success in our mission


Basic Qualifications: 

  • JD degree and a graduate degree in a life sciences discipline
  • 5+ years of experience in life sciences patent preparation and prosecution, including significant experience with large molecule therapeutics in the past 2 years
  • Self-motivated and creative patent attorney
  • Active registration in good standing to practice before the U.S. Patent and Trademark Office
  • Active member in good standing of at least one state bar
  • Advanced knowledge of domestic and international intellectual property laws, regulations, and processes relating to patents
  • Ability to independently manage, with the assistance of outside counsel, global patent portfolios related to protein therapeutics
  • Excellent written and oral communication skills
  • Naturally open, transparent, and thrives in teamwork environment


Preferred Qualifications:

  • Advanced degree in the life sciences
  • Experience as in-house counsel in biotech and/or pharma industry


Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.

Salary Range: $243,000.00 to $292,333.00. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Denali offers a competitive total rewards package, which includes a 401k, healthcare coverage, ESPP and a broad range of other benefits. Learn more at

*This compensation and benefits information is based on Denali’s good faith estimate as of the date of publication and may be modified in the future. 

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