Neurodegenerative diseases are one of the largest medical challenges of our time. Denali Therapeutics is a biotechnology company dedicated to developing breakthrough therapies for neurodegenerative diseases through our deep commitment to degeneration biology and principles of translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that scientific discovery energetically applied to translational medicine is the key to delivering effective therapies to patients.

We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.

The Opportunity

Denali Therapeutics is seeking a highly organized and motivated person to manage our facility operations. The position requires strong background in supporting office, R&D and laboratory set up and operations in a GMP/GXP environment.  Extensive experience managing overall effective operations of Facilities.


  • Direct complex, deadline driven projects across multiple vendors while delivering facility related corporate services to the highest standard
  • Participate and lead space planning activities
  • Serve as point of contact for vendors, contractors, service providers and building management
  • Partner with EH&S technical staff to maintain a safe working environment
  • Develop and manage processes and SOPs around lab equipment management
  • Participate in company risk prioritization and management processes
  • Develop and implement business continuity planning for lab and office (including any evolution of COVID19 plans in collaboration)
  • Identify new opportunities for optimizing office & lab processes and space and maximize technologies to support the budget and scale processes
  • Drive renovation projects and office/lab moves
  • Maintain all pertinent permitting
  • Create and provide a safe and secure work environment for all employees
  • Ensure compliance with all applicable health and safety laws and regulations
  • Cultivate and maintain strong, beneficial relationships with vendors and other support service functions within the company

Basic Qualifications

  • Bachelor’s degree in engineering or related field
  • 8+ years’ experience managing complex construction projects in a highly regulated environment
  • Demonstrated ability to deliver construction projects within specified timelines
  • Extensive experience with GXP system implementation, procedures, and documentation
  • Outstanding organizational, communication and interpersonal skills

Preferred Qualifications

  • Master’s degree
  • Previous Biotech/Pharma experience

Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.



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