Cygnal, a new biology platform company, was founded by Flagship Pioneering to pioneer the field of exoneural biology – the impact of the peripheral nervous system on cancer, the immune system, metabolism, and regeneration. The company is applying cutting-edge neuroscience to elucidate novel therapies to treat cancer progression and metastasis, autoimmune conditions, inflammation, and other diseases.

Flagship Pioneering conceives, creates, resources, and develops first-in-category life sciences companies to transform human health and sustainability. Since its launch in 2000, the firm has applied a unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in over $30 billion in aggregate value. To date, Flagship is backed by >$3 billion of aggregate capital commitments, of which over $1.4 billion has been deployed toward the founding and growth of its pioneering companies alongside >$10 billion of follow-on investments from other institutions. The current Flagship ecosystem includes Denali Therapeutics (NASDAQ: DNLI), Evelo Biosciences (NASDAQ: EVLO), Moderna Therapeutics (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), Seres Therapeutics (NASDAQ: MCRB), and Syros Pharmaceuticals (NASDAQ: SYRS).

The Research Project Manager provides project management support to Cygnal’s Discovery Biology and Platforms team, managing activities such as adherence to experimental timelines, prioritization and strategy for our growing set of pre-clinical projects, and organization of ongoing meeting needs. More broadly, the Project Manager will work closely with Cygnal’s research teams (leadership and scientists) to manage and coordinate activities that span multiple functions and research projects.


  • Establish strong partnerships with key cross-functional stakeholders and work with them to shape the overall strategy, goal setting & successful execution of research-stage projects
  • Assist with translating high-level research plans into specific activities for Cygnal’s scientists to execute
  • Manage overall timelines, Gantts, and schedules associated with Cygnal’s research plans and programs
  • Implement processes, tools, templates, and dashboards to track progress and ensure timely work
  • Manage research project meetings, e.g. develop and distribute agendas and meeting minutes to ensure presenters are prepared, objectives are clear, and the outcomes are documented for communication to the team and broader organization
  • Proactively seek out opportunities for organizational improvement (e.g. meeting structure, information storage flow, communication, etc.)
  • Anticipate execution and timeline risks, appropriately troubleshooting or escalating to leadership
  • Proactively identify risks and gaps; resource bottlenecks and work with teams to develop and implement mitigation plans
  • Ensure scientists, equipment, lab time, inventory, and vendors are coordinated for projects
  • Manage communications (e.g., decisions requiring input, updates) to project stakeholders
  • Assist scientists with preparation of reports, presentations, and readouts to support technical reviews
  • Contribute to company initiatives, as needed, to support the effective scaling of Program & Portfolio capabilities


  • Bachelor’s degree in a scientific field; Masters or PhD in a scientific field a plus
  • Minimum (2) + years’ experience in project management & coordination
  • Experience working in a matrix environment and managing interactions between internal team members; excel at relationship building
  • Highly collaborative team player who fosters open communication and facilitates mutual understanding and cooperation between all stakeholders
  • Demonstrated ability to effectively manage competing priorities
  • Experience providing support to technical teams in biotech and/or drug development
  • Highly detail oriented with excellent communication, organizational, and interpersonal skills
  • Proficiency with Microsoft Office, including Outlook, PowerPoint, SharePoint, and Project
  • Passion, humility, and excitement for doing whatever it takes to drive research forward


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