Flagship Pioneering conceives, creates, resources, and develops first-in-category life sciences companies to transform human health and sustainability. Since its launch in 2000, the firm has applied a unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in over $30 billion in aggregate value. To date, Flagship is backed by >$3 billion of aggregate capital commitments, of which over $1.4 billion has been deployed toward the founding and growth of its pioneering companies alongside >$10 billion of follow-on investments from other institutions. The current Flagship ecosystem includes Denali Therapeutics (NASDAQ: DNLI), Evelo Biosciences (NASDAQ: EVLO), Moderna Therapeutics (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), Seres Therapeutics (NASDAQ: MCRB), and Syros Pharmaceuticals (NASDAQ: SYRS).
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Generate ideas and design experimental plans for novel screening platforms
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Generate ideas and design experimental plans for target identification and validation in vitro and in vivo
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Execute experiments, generate and analyze data, and communicate data to scientific team and executive management
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Lead and collaborate with other scientists and research associates to achieve company objectives
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Manage external research relationships with academic and commercial partners
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Experience in pooled/arrayed CRISPR screening and/or other novel screening technologies
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Experience in target identification and validation, using both genetic tools and compounds for target manipulation.
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Experience in innovative assay development, e.g. co-culture assays, high throughput imaging read-outs, etc.
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Experience in design and execution of in vivo translational studies.
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Creative, independent, self-motivated and curious.
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Highly adaptable and responsive to technical and business opportunities and needs – comfortable delivering against challenging commitments.
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Excellent communication and presentation skills, capable of conveying information in a clear and thorough manner.
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Confident, execution focused, team oriented, with an ability to thrive in an entrepreneurial environment.
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PhD or equivalent in the biological sciences, bioengineering, or related field.
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5+ years of relevant laboratory experience, in academic, pharmaceutical or biotechnology settings.
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Demonstrated ability in working with highly skilled teams in a fast-paced, entrepreneurial and technical setting.