Company Overview
At Clasp Therapeutics, we are revitalizing immuno-oncology’s promise with next-generation T cell engagers (TCEs). Our novel TCE therapeutics enable a patient’s T cells to identify and specifically destroy tumor cells with absolute precision. Our medicines’ high level of precision and specificity essentially eliminate the likelihood of on-target off-tumor toxicities that have occurred with other TCEs. We have targeted our molecules to hard-to-treat tumors bearing common cancer driver mutations. Our specific platform structure targets mutated protein fragments, or peptides, that are displayed by specialized HLA and are designed to draw T cells into close contact with tumor cells. The resulting immune synapse is highly similar to a natural HLA molecule-T cell receptor interface with a high level of sensitivity, triggering T cells to destroy tumor cells. This approach enables a highly genetically selective paradigm where every patient has the opportunity to respond to treatment.
Founded in 2020, we are focused on bringing the outstanding science from our world-class founders to patients. In 2023, Clasp closed a $150 million Series A financing round led by Catalio Capital Management, Third Rock Ventures, and Novo Holdings. Clasp has created a vibrant culture with people who are committed to our mission in both our Cambridge, MA, and Rockville, MD sites.
Position Summary:
We are seeking a motivated and enthusiastic college student to join our team in the field of antibody discovery and protein engineering. This position offers a unique opportunity to gain hands-on experience in a dynamic laboratory environment, focusing on bringing automation and high throughput approaches to classical biochemical and molecular biology problems with the goal of discovering truly cancer-specific therapeutics.
Key Responsibilities:
- Learn classical molecular biology and biophysical techniques (DNA manipulation and protein production/characterization) and assist in building automation workflow to improve throughput capabilities using computational and robotic approaches.
- Learn and participate in protein purification process and conduct protein quality and kinetic analyses.
- Collaborate with team members to support ongoing research and development projects.
- Communicate effectively with team members to report findings and progress.
- Shipment/storage of final reagent materials.
Qualifications:
- Currently a rising senior, enrolled in a college program related to engineering, biochemistry, biology, chemistry etc.
- Prior experience working in a lab.
- Strong interest in automation, computational biology and/or robotics, biologics.
- Excellent communication skills and a proactive approach to learning.
- Ability to work independently and as part of a team.
- Detail-oriented with strong organizational skills.
What We Offer:
- Hands-on experience in a leading-edge laboratory environment.
- Mentorship from experienced professionals in the field.
- Opportunities to learn all aspects of biologics discovery.
- A collaborative and supportive work culture.
Clasp Therapeutics is an equal opportunity employer committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, nationality, national or ethnic origin, civil status, age, citizenship status, sexual orientation, disability, marital or registered civil partnership status, pregnancy or parental status, gender identity, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you may need.
Note to Employment Agencies: Please, no phone calls or emails to any employee of Clasp Therapeutics about our openings. All resumes submitted by search firms/employment agencies to any employee at Clasp Therapeutics via email, the internet or in any form and/or method will be deemed the sole property of Clasp Therapeutics, unless such search firms/employment agencies were engaged for the position and a valid agreement is in place. In the event a candidate is hired who was submitted outside the Clasp Therapeutics agency engagement process, no fee or payment of any kind will be paid.
