The Chan Zuckerberg Initiative was founded by Priscilla Chan and Mark Zuckerberg in 2015 to help solve some of society’s toughest challenges — from eradicating disease and improving education to addressing the needs of our local communities. Our mission is to build a more inclusive, just, and healthy future for everyone.

The Team

CZI supports the science and technology that will make it possible to cure, prevent, or manage all diseases by the end of this century. While this may seem like an audacious goal, in the last 100 years, biomedical science has made tremendous strides in understanding biological systems, advancing human health, and treating disease. 

We build open source software tools and leverage artificial intelligence to accelerate the pace of biomedicine. We fund scientific research worldwide to advance the frontiers of knowledge. And we launched a family of institutes to do research that can’t be done in conventional environments. Each aspect is essential to our approach to building for the long term.

CZI’s work in science includes grantmaking programs, open-source software development, and close collaboration with its partner institutes at the Chan Zuckerberg Biohub Network. The CZ Biohub Network includes the San Francisco, Chicago, and New York Biohubs as well as the Chan Zuckerberg Imaging Institute. CZI also collaborates with institutional partners like the Kempner Institute for the Study of Natural & Artificial Intelligence at Harvard University. Join us in accelerating science.

The AI/ML team is funding and building one of the largest computing systems dedicated to nonprofit life science research in the world. This new effort will provide the scientific community with access to predictive models of healthy and diseased cells, which will lead to groundbreaking new discoveries that could help researchers cure, prevent, or manage all diseases by the end of this century.

The Opportunity

We seek a world-class technology leader to bring together the Engineering Infrastructure, Security, and Information Technology Systems into an efficient and effective set of services across CZI and CZ Science.

Reporting to the COO, this new role will develop and execute the vision and strategy to enable the technology investments and core business operations to achieve our impact and collaboration objectives. This includes supporting:

  • CZI’s core operations - all of the business systems and IT needs to power the G&A capabilities required to operate CZI as a technology organization, a grant-making organization, and supporter of new, highly collaborative institutes that are part of  CZ Science and CZI’s core software technology teams - across the Science and Education technology teams, the shared engineering, data, and security infrastructure needed to drive developer productivity and efficiency
  • CZI’s AI compute resources - managing the cloud and cluster resources to create the largest technology industry-standard compute resources for biomedical academic researchers across CZ Science, CZI’s software teams, and beyond

This is an excellent opportunity for an outstanding leader, inspired by CZI’s mission, with a passion for the potential of technology to enable organizations to operate effectively, including accelerating scientific progress and applying technology to changing education.

What You'll Do

  • Develop an Org-Wide Technology Strategy: Creating a strategy that supports the overall goals of CZI, considering the evolution and priorities across CZI and CZ Science, including science institutes and Biohubs and science and education technology teams.
  • Align Technology with Strategic Priorities: Ensuring technology spending aligns with organizational goals and managing technology budgets effectively.
  • Lead Core Functional Teams: Managing teams across Information Technology, Business Systems, Security, High-Performance Scientific Computing, Engineering Infrastructure, AI/ML Operations, and Data Engineering.
  • Adapt Organizational Design: Modifying the organization's structure and team culture within functional areas to promote innovation, effective resource sharing, and rapid iteration.
  • Develop AI Compute Infrastructure: Building AI infrastructure for biomedical research, aligning with technology industry standards, and fostering novel academic collaborations.
  • Support Cloud-Based Software Development: Enhancing developer productivity and scalability for CZI’s Science and Education technology teams.
  • Ensure Security and Compliance: Making sure all technology systems and platforms are secure and compliant with relevant standards.
  • Establish Reliable and Scalable Infrastructure: Guaranteeing the technology infrastructure is reliable, scalable, and efficient, meeting the evolving needs of CZI.
  • Secure Vendor and Partner Relationships: Developing and maintaining relationships with technology vendors and service providers for optimal technology investment value.
  • Collaborate with Leadership Teams: Working with initiative, operations, and institutes leadership teams to develop technology solutions that support CZI’s mission.
  • Monitor Industry Trends: Keeping an eye on emerging technologies and industry trends to leverage new technologies for  differentiated impact

What You'll Bring

  • Extensive Leadership Experience: Over 15 years in technology leadership roles including experience in a scientific computing or scientific research  environments, showcasing a successful track record in guiding and managing sizable, multifaceted technology teams.
  • Expertise in Cloud Computing and Data Services: A deep understanding of and experience with leading cloud computing platforms, data services, and enterprise application architecture.
  • Communication and Interpersonal Skills: Exceptional communication ability, fostering effective collaboration with a diverse range of stakeholders throughout the organization.
  • Customer Service Orientation: A strong commitment to customer service within the Information Technology sector, emphasizing active listening to stakeholders' needs and delivering high-quality systems and services.
  • Business Acumen and Strategic Alignment: Proficient in aligning technology strategies with the organization's broader business goals and objectives, demonstrating strong business insight.
  • Budget Management and Strategic Investment: Proven experience creating, managing, and strategically deciding on technology budgets and investments.
  • Analytical and Problem-Solving Proficiency: Robust analytical skills coupled with the ability to solve complex technology challenges effectively.
  • Multidisciplinary Team Experience: A history of working with and understanding the unique needs of organizations and teams across multiple disciplines, showing a commitment to appreciating cultural, structural, and technical diversity.


The Redwood City, CA base pay range for this role is $435,000 - $696,000. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process. Pay ranges outside Redwood City are adjusted based on cost of labor in each respective geographical market. Your recruiter can share more about the specific pay range for your location during the hiring process.

Benefits for the Whole You 

We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible. 

  • CZI provides a generous 100% match on employee 401(k) contributions to support planning for the future. 
  • Annual funding for employees that can be used most meaningfully for them and their families, such as housing, student loan repayment, childcare, commuter costs, or other life needs.
  • CZI Life of Service Gifts are awarded to employees to “live the mission” and support the causes closest to them.
  • Paid time off to volunteer at an organization of your choice. 
  • Funding for select family-forming benefits. 
  • Relocation support for employees who need assistance moving to the Bay Area
  • And more!

Commitment to Diversity

We believe that the strongest teams and best thinking are defined by the diversity of voices at the table. We are committed to fair treatment and equal access to opportunity for all CZI team members and to maintaining a workplace where everyone feels welcomed, respected, supported, and valued. Learn about our diversity, equity, and inclusion efforts. 

If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.

Explore our work modesbenefits, and interview process at



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