Founded by Priscilla Chan and Mark Zuckerberg in 2015, the Chan Zuckerberg Initiative (CZI) is a new kind of philanthropy that’s leveraging technology to help solve some of society’s toughest challenges – from eradicating disease, to improving education. Across our core initiatives of Science and Education, we’re pairing engineering with grantmaking, impact investing, policy work, and advocacy, to progress in our mission of building an inclusive, just and healthy future for everyone.

Our Values

We believe we can help build a future for everyone.

  • We aim to be daring, but humble:  We look for bold ideas — regardless of structure and stage — and help them scale by pairing engineers with subject matter experts to build tools that accelerate the pace of social progress.
  • We want to learn fast, but build for the long-term: We want to iterate fast and help bring new solutions to the table, but we also realize that important breakthroughs often take decades, or even centuries.
  • Stay close to the real problems: We engage directly in the communities we serve because no one understands our society’s challenges like those who live them every day.  

Our success is dependent on building teams that include people from different backgrounds and experiences who can challenge each other's assumptions with fresh perspectives. To that end, we look for a diverse pool of applicants including those from historically marginalized groups — women, people with disabilities, people of color, formerly incarcerated people, people who are lesbian, gay, bisexual, transgender, and/or gender nonconforming, first and second generation immigrants, veterans, and people from different socioeconomic backgrounds.

CZI also supports multiple work options. Learn more about our philosophy and approach here.

The Opportunity

In our Science Initiative, our mission is to support science and technology that will help make it possible to cure, prevent, or manage all diseases by the end of the century. Interdisciplinary teams of physicians, biologists, computational scientists, and engineers can expand our understanding of the human body and illness — the very science behind medicine. CZI fosters collaboration between scientists and engineers, develops tools and technologies, and builds support for basic scientific research. 

Some Science Initiative tools include:

  • Aspen - an open-source software tool for departments of public health that helps respond to and slow the spread of infectious disease, including COVID-19 and its variants
  • IDseq - an open-source, real-time pathogen detection dashboard for scientists that helps identify and prevent infectious disease outbreaks around the world
  • napari - an open-source interactive, multi-dimensional image viewer for python
  • cellxgene - an open-source interactive data explorer for single-cell transcriptomics data
  • Meta - a semantic discovery tool that provides a faster way to understand, organize and explore science through personalized feeds

Infectious disease represents 20% of human deaths worldwide. As a Product Application Scientist on the Infectious Disease team, you will have the opportunity to transform the way that infectious disease is identified, treated, and managed, by working in close partnership with both CZI’s product development team and scientists around the world who use our tools. You will develop a close pulse on our community, engaging with a global network of forward-thinking and passionate biomedical researchers and public health experts.

The Infectious Disease product team has developed two tools for the scientific and public health community:


Developed in response to the global COVID-19 pandemic, Aspen is a software tool for departments of public health to track and manage outbreaks in their local jurisdictions. For example, outbreaks in schools, skilled nursing facilities, factories, and farms. With Aspen, departments of public health can use genomic epidemiology to identify the potential source and transmission of an outbreak, and then take measured steps to contain the spread of disease. Today Aspen is focused on COVID-19 and its new variants, but, in the near future, will also be used for tracking and managing other infectious diseases of concern such as tuberculosis.


Long before COVID-19, infectious disease has been a priority for scientists and public health experts around the world. IDseq was developed to provide a platform for scientists to leverage the power of metagenomics sequencing to identify disease agents in their populations and detect outbreaks early. By hosting this no-code tool for free in the cloud, IDseq aims to democratize use of this technology, empowering scientists around the world to reduce the threat of infectious disease at scale. You can read about how IDseq has helped scientists in Bangladesh determine the cause of a meningitis outbreak, and researchers in Cambodia confirm the country’s first case of COVID-19.

You will

  • Establish, nurture, and maintain relationships with key research and public health communities. Currently we work with infectious disease scientists in low-middle income countries and departments of public health in the US.
  • Work hands-on with researchers and public health professionals to ensure that they can successfully utilize Aspen and IDseq in their work and derive insights that impact their local communities.
  • Help researchers learn about metagenomics and genetic epidemiology so that they can gain the skills and knowledge they need to take full advantage of Aspen and IDseq to address their priority investigations.
  • Develop and deliver innovative resources for onboarding and training researchers and public health practitioners on Aspen and IDseq, providing them with the ability to independently run analyses and interpret their results with confidence.
  • Identify and lead opportunities to build a scientific community around metagenomics, genetic epidemiology, and our tools, so that users have a place to share ideas and collaborate with each other.
  • Lead workshops, provide scientific and technical support, and develop training materials that build the capabilities of users of our tools.
  • Engage in community outreach with researchers to generate awareness and enable their use of Aspen and IDseq through remote and on-site lab visits, and presentations at seminars, meetings, and conferences.
  • Embed within the CZI Infectious Disease Team to represent the voice of our public health and research users, help frame product requirements, and partner on implementations and designs, in order to ensure that the tools that we build meet the needs of the scientific community.
  • Distill and communicate insights learned from working with users, in order to drive both technical implementations and longer term strategy.
  • Develop an understanding of the scientific and technical landscape within genomic epidemiology, metagenomics, and infectious disease and share those learnings with the team to help inform our approach to product development.
  • (nice to have) When needed, build computational tools and develop scripts to enable the use of CZI products

You have

  • Strong affinity for CZI Science’s mission: supporting the science and technology that will make it possible to cure, prevent, or manage all diseases by the end of this century.
  • Drive and commitment to empower scientists as they adopt new tools and technology.
  • Previous experience in engaging with scientists and public health practitioners, and/or working directly with partners or customers in the life sciences.
  • Ability to collaborate and communicate effectively with a diverse set of cross-functional teammates and partners (internal and external).
  • Excellent written and verbal communication skills in scientific and nonscientific settings.
  • PhD / MS / MPH / MD in genomics, epidemiology, or infectious disease.
  • (nice to have) An understanding of public health surveillance and response.
  • (nice to have) Hands-on experience in data analysis and programming languages
CZI believes that vaccines are one of the most powerful tools to fight COVID-19 and save lives. It aligns to our mission and work to cure, manage, and prevent disease. Proof of completed COVID-19 vaccination will be required for all applicants and employees to come onsite to a CZI facility. CZI will consider exceptions to this policy for medical or religious reasons on an individualized basis.

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