Founded by Priscilla Chan and Mark Zuckerberg in 2015, the Chan Zuckerberg Initiative (CZI) is a new kind of philanthropy that’s leveraging technology to help solve some of society’s toughest challenges – from eradicating disease, to improving education. Across our core initiatives of Science and Education, we’re pairing engineering with grantmaking, impact investing, policy work, and advocacy, to progress in our mission of building an inclusive, just and healthy future for everyone.

Our Values

We believe we can help build a future for everyone.

  • We aim to be daring, but humble:  We look for bold ideas — regardless of structure and stage — and help them scale by pairing engineers with subject matter experts to build tools that accelerate the pace of social progress.
  • We want to learn fast, but build for the long-term: We want to iterate fast and help bring new solutions to the table, but we also realize that important breakthroughs often take decades, or even centuries.
  • Stay close to the real problems: We engage directly in the communities we serve because no one understands our society’s challenges like those who live them every day.  

Our success is dependent on building teams that include people from different backgrounds and experiences who can challenge each other's assumptions with fresh perspectives. To that end, we look for a diverse pool of applicants including those from historically marginalized groups — women, people with disabilities, people of color, formerly incarcerated people, people who are lesbian, gay, bisexual, transgender, and/or gender nonconforming, first and second generation immigrants, veterans, and people from different socioeconomic backgrounds.

The Opportunity

The Science Initiative at CZI supports science and technology that will help make it possible to cure, prevent, or manage all diseases by the end of the century. Our support takes many forms: grantmaking, collaborating directly with researchers, developing technology and tools, and building support for scientific research. In the science initiative, CZI fosters collaboration between scientists and engineers, develops tools and technologies, and builds support for basic scientific research.   Interdisciplinary teams of physicians, biologists, computational scientists, and engineers can expand our understanding of the human body and illness — the science behind medicine.

The Science Team is seeking a Science Program Manager to support our efforts around neurodegenerative disease through the Neurodegeneration Challenge Network. Our goal for this project is to develop a new kind of collaborative network around the fundamental biology of neurodegenerative diseases--one that brings new ideas and new people into the field, supports them with well-validated tools and resources, and challenges them to look at this problem from a cross-disease perspective. You will join a growing team working on CZI’s Neurodegeneration Program and will also work collaboratively across the Science Initiative’s major programs in Imaging, Single-Cell Biology, Open Science and Patient-directed research

You will

  • Serve as a Program Manager for Neurodegeneration with a specific focus on developing and supporting the Neurodegeneration Challenge Network project. This will involve contributing to the scientific vision for the Network; mentoring participating scientists, supporting NDCN’s open science strategy and practice; contributing to the planning, execution and evaluation of grants and projects across the Challenge Network.
  • Contribute to NDCN’s efforts to promote open science and shared resource development. Manage investigator-led collaborative Working Groups strategy and project manage collaborative resource development projects emerging from the Network labs, working with teams to develop project priorities and plans and helping drive successful execution of these projects.
  • Support the management of teams’ grants and partnership portfolios. This will involve working with our grantmaking, operations and finance teams, as well as our grantees and external partners.
  • Work collaboratively with Science program staff, computational biologists and engineering team on projects in support of the Challenge Network
  • Serve as a liaison to the scientific community around neurodegeneration efforts and CZI Science

You have

  • PhD degree or equivalent experience in an area of biomedical sciences, ideally in a field relevant to neurodegeneration or aligned with CZI’s current areas of focus around genomics, quantitative biology, systems biology, cell biology. The successful candidate will need to be able to engage with the scientific scope of the Neurodegeneration Challenge Network on a deep level. The ideal candidate will have broad interests, passion and ability to learn and transfer expertise across disciplines.
  • Experience in managing and/or mentoring collaborations of scientists. This could be previous experience as a staff scientist, or in another area of scientific practice such as government, publishing, biotechnology, a scientific research foundation, or community-building activities, that involve working with collaborations and/or networks of scientists.
  • A passion for science and supporting scientists in the work they do. Understanding how biomedical researchers, in particular in academic settings, think and work and the challenges they face
  • Strong project management, collaboration and organizational skills. Ability to move forward collaborative projects successfully, engaging multiple stakeholders and often balancing multiple priorities and projects.
  • Excellent written and verbal communication skills. You will be writing and editing both internal and external written materials for supporting grants and strategic communications.
  • Creativity and flexibility, strong problem-solving skills, and ability to work collaboratively in a dynamic start-up environment

Apply for this Job

* Required


Voluntary Self Identification

Applicant Privacy Notice

To learn more about how we use the information you submit, please see our Privacy Notice for Job Applicants.


Equal Employment Opportunity & Diversity

We care deeply about equal opportunity and diverse representation in our workforce. In support of these goals, we invite applicants to voluntarily provide demographic information.  This information will not be used in hiring decisions; individuals seeking employment at CZI are considered without regard to race, color, religion, national origin, age, marital status, ancestry, physical or mental disability, veteran status, gender identity, sexual orientation, or any other protected class. See CZI’s Equal Employment Opportunity Policy

Completing the below is voluntary, but we encourage you to answer, since this information helps CZI evaluate and build our recruiting programs to help us achieve our goal of building a diverse, equitable and inclusive organization. We may also use responses to this form to comply with certain government reporting obligations. All responses will be shared only with limited personnel, who will use that information only for the purposes described in this paragraph. 

If you have any additional questions about why we ask this, what we do with the data, or to share suggestions for improvement, feel free to reach out to


Reasonable Accommodation Notice

CZI provides (and state and federal law requires) reasonable accommodations to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job (reach out to your recruiter or Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment.


Government reporting relies on certain demographic definitions, however, within that framework CZI has attempted to provide an opportunity for additional nuance by way of expanding our questions and providing open text fields for you to add further detail as desired.  

What is your gender?

Are you transgender?

Are you a member of the LGBTQ community?

Please identify your veteran status.

What is your race/ethnicity? (please check one; you may write in further detail at the end of this question)