Founded by Dr. Priscilla Chan and Mark Zuckerberg in 2015, the Chan Zuckerberg Initiative (CZI) is a new kind of philanthropy that’s leveraging technology to help solve some of the world’s toughest challenges – from eradicating disease, to improving education, to reforming the criminal justice system. Across three core Initiative focus areas of Science, Education and Justice and Opportunity,  we’re pairing engineering with grantmaking, impact investing, policy work, and movement building, to help build an inclusive, just and healthy future for everyone.

Our Values

We believe we can help build a future for everyone.

  • We aim to be daring, but humble:  We look for bold ideas — regardless of structure and stage — and help them scale by pairing engineers with subject matter experts to build tools that accelerate the pace of social progress.
  • We want to learn fast, but build for the long-term: We want to iterate fast and help bring new solutions to the table, but we also realize that important breakthroughs often take decades, or even centuries.
  • Stay close to the real problems: We engage directly in the communities we serve because no one understands our society’s challenges like those who live them every day.  

Our success is dependent on building teams that include people from different backgrounds and experiences who can challenge each other's assumptions with fresh perspectives. To that end, we look for a diverse pool of applicants including those from historically marginalized groups — women, people with disabilities, people of color, formerly incarcerated people, people who are lesbian, gay, bisexual, transgender, and/or gender nonconforming, first and second generation immigrants, veterans, and people from different socioeconomic backgrounds.

The Opportunity

By pairing engineers with leaders in our Education, Science, and Justice and Opportunity teams, we can bring technology to the table in new ways to help drive solutions. We are uniquely positioned to design, build, and scale software systems to help educators, scientists, and policy experts better address the myriad challenges they face. 

In our Science Initiative, our mission is to support science and technology that will help make it possible to cure, prevent, or manage all diseases by the end of the century. Interdisciplinary teams of physicians, biologists, computational scientists, and engineers can expand our understanding of the human body and illness — the very science behind medicine. CZI fosters collaboration between scientists and engineers, develops tools and technologies, and builds support for basic scientific research. 

Some Science Initiative example projects include:

  • napari - an open-source interactive, multi-dimensional image viewer for python
  • IDseq - a metagenomics platform focused on delivering insights in infectious disease
  • Starfish - an open-source image processing framework, enabling access to multiplex image-based transcriptomics analysis
  • cellxgene - an open-source interactive data explorer for single-cell transcriptomics data
  • Meta - a semantic discovery tool that provides a faster way to understand, organize and explore science through personalized feeds

As a Senior Software Engineer on the Single-Cell Engineering Team, you will provide tech leadership for a team building cloud-based tools and infrastructure that support a global community of scientists and engineers advancing the frontiers of single-cell biology. The team builds end-to-end software solutions, including petabyte scale data archives, analysis pipelines, and visualization systems, with a domain focus on molecular and cellular-scale measurement of biological systems.

You will

  • Provide technical leadership to software development teams towards delivering value to users
  • Mentor junior engineers
  • Architect and develop software applications to manage collection, storage, analysis and visualization of biological assay data
  • Work in a multi-disciplinary team, with engineers, scientists, product managers, designers and user researchers, to define product plans and strategy
  • Collaborate directly with external open source partners, scientific collaborators, and early adopters
  • Participate in building single-cell data APIs, visualization tools, and analysis platforms

You have

  • 5+ years of software design, development, and production experience
  • 3+ years using relevant technologies, which include building backend microservices on public cloud-based infrastructure (Amazon Web Services, Google Cloud Platform, Azure, or equivalent), high-scale databases, web front-end (HTML/CSS, data visualization tools), etc.
  • Demonstrated ability to learn and use new methods and tools, define project requirements, ship completed projects
  • Demonstrated ability to mentor junior engineers
  • Excellent written and verbal communication skills
  • Experience with the Python programming language, genomics, open source software communities, and defensive application development (computer security) are all pluses

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