Centrillion Biosciences is developing cutting edge genomic technologies. We have advanced research laboratories in Palo Alto, CA; Portland, OR; Hangzhou, China and Hsinchu, Taiwan for conducting research in bioinformatics, genomics, chemistry, biochemistry, and molecular biology. The following position is for our Palo Alto facility. Centrillion Biosciences is seeking a highly motivated and skilled Research Scientist – Nucleic Acids Chemistry to join our chemistry team.
Plan and execute applied research experiments involving: Synthesis, modification and characterization of modified nucleotides, nucleoside polyphosphates and oligonucleotides
Preparation of fluorescent dye conjugates of nucleotides and oligonucleotides.
Materials modification and characterization for solid phase synthesis
Collaborate with and/or supervise other scientists & engineers on joint projects.
Documentation of experimental work; analysis of data; documenting and presenting results
Preparation of written methods and SOPs
Operation and maintenance of laboratory & analytical equipment
Support R&D and Pilot Manufacturing Operations and QC
Ph.D. in organic chemistry, with extensive training and practical laboratory experience in organic synthesis, physical organic and bio-organic chemistry.
Experience with nucleoside, nucleotide, and solid-phase oligonucleotide synthesis.
Experience preparing fluorescent dye conjugates of nucleotides and oligonucleotides.
Proficient in the use of methods of instrumental chemical analysis, such as NMR, HPLC, MS, FTIR, is essential.
Working knowledge and practical experience with polymer and surface chemistry is strongly desired.
Demonstrated ability to plan and execute independent and collaborative research projects.
Demonstration of goal-oriented, hands-on and innovative approach to problem solving.
Co-authorship on one or more publications in peer-reviewed scientific journals.
She/he will be required to develop additional competencies, and apply practical skills and knowledge to solving a variety of applied scientific and technical problems.
All applicants, please send publication list and any additional description of research experience, like, manuscripts, abstracts and meeting presentations, with your application.