On January 11, 2021, we announced our intent to separate our severe genetic disease and oncology businesses into differentiated and independent publicly traded companies. We will retain focus on severe genetic disease (SGD) and will launch our oncology business (“Oncology Newco”) as a new entity, with the completed transition expected by the end of 2021.

 

ABOUT THE NEST

At bluebird, only two things matter - patients and our people. When you join the nest, you're not just landing a new gig, you become a part of a flock that's soaring to new heights. We’re 1100+ doers, thinkers and collaborators across the globe with a strong sense of our values and our purpose. Our innovation and sustainability are rooted in the diversity of our teams and results are achieved through cooperation and the incorporation of multiple points of view. This is personal and we approach every challenge with radical care. The time is now to rise up and recode the science, the systems, and the status quo.

ABOUT THE FLOCK

The Process Sciences & Innovation flock is all about working collaboratively to get sh*t done! Together we are developing and characterizing our processes to manufacture high quality stem cells in an innovative and scalable way for our patients. We develop the gene therapy manufacturing platform and chaperone it from pre-clinical to commercial manufacturing phases in collaboration with other teams across Technical, Development and Operations, Research and Clinical. One aspect of this are core services, which include the generation of representative cellular materials to support our partner groups and testing of in-process retains. We are looking for a motivated individual to develop junior scientists, work with our cross-functional partners, optimize and drive these core services! With one approved product (Zynteglo™) and multiple clinical stage candidates, there is a wealth of growth opportunities for driven individuals to make a significant impact in patients’ lives. Come join our incredibly talented team of birds and learn more about how you can drive scientific advancements that ultimately serve patients with gene-modified stem cell products.

 

HOW YOU’LL FLY

As a Process Sciences & Innovations bird reporting to Associate Director, Process Sciences & Innovation, you’ll help bring more patients their bluebird days by:

  • Leading a small team to test in-process retains and generate cellular material (from apheresis material through to LVV-transduced cells) to support development, qualification, and validation activities of our internal collaborators.
  • Training and developing junior scientists in the execution and analysis of their work and providing mentorship in their career development.
  • Collaborating with members of our partner groups, including research, analytical development, and quality, to identify material needs and manage requests.
  • Analyzing, trending, and summarizing data to present to stakeholders, provide feedback on process improvements and author reports.
  • Designing and performing experiments involving the isolation, transduction, and cryopreservation of gene modified hematopoietic stem cells for the treatment for hematological malignancies.
  • Driving a culture of quality through documentation, processes and systems.

WHAT YOU’LL BRING

You’re the bird we’re looking for if you:

  • Have a BS with 8+ years of directly related experience or MS with 5+ years of directly related experience, or PhD with 0+ years of experience in cellular process development or manufacturing. Degree emphasis in Chemical Engineering, Biochemistry, Bioengineering, Biology, or related field preferred.
  • Previous experience managing/mentoring associate scientists in a laboratory setting is required.
  • Demonstrated ability to collaborate and communicate across organizational levels and disciplines, with excellent communication and inter-personal skills is required.
  • Expertise in using a laboratory notebook and familiarity with good documentation practices (GDP) is required.
  • Experience authoring technical documents (protocols, reports, SOPs) is preferred.
  • Experience managing a laboratory and multiple projects is preferred.
  • Expertise in aseptic tissue/cell culture is required. Experience with the culturing of primary human hematopoietic stem cells is preferred.
  • Experience with large scale, closed system manufacturing of therapeutic cell and/or gene therapy products from whole blood, apheresis, or bone marrow is preferred and a broad knowledge of common cellular therapy equipment such as Sepax, controlled rate freezers, and cell separation technologies (CliniMACS and other technologies) is desirable.
  • Strong background in a variety of biological assays such as flow cytometry, qPCR, ELISA, FACS, and Luminex is preferred.
  • Demonstrated experience with statistical software (JMP, Minitab, Prism or others) is desirable


All our birds embrace the principles of the bluebird bio culture:  b colorful, b cooperative, b yourself.

bluebird bio is deeply committed to fostering an environment where diversity and inclusion are not only valued, but prioritized. We believe a diverse and inclusive community empowers us to act courageously, care deeply, and dream boldly to impact people in big ways.  Diverse viewpoints bring diverse capabilities which strengthen our focus and fuel our growth.

bluebird is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment.  All applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, veteran status or any other applicable legally protected characteristics.

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