Do you want to join one of the fastest-growing molecular diagnostics companies to help transform prenatal and oncology diagnostics that can affect millions of patient lives?

BillionToOne, ranked at the top 5% of Y Combinator companies with $200M+ in funding from prominent VC firms, has developed a DNA molecular counter that increases the cell-free DNA diagnostics resolution by over 1,000 fold. BillionToOne's first product, UNITY™ is the first and only prenatal screen that directly assesses a baby's risk for common and severe recessive gene disorders such as cystic fibrosis and sickle cell, and chromosomal abnormalities like down syndrome from a single tube of blood from the pregnant mother.

We are looking for a Process Engineering Associate to join our growing superstar Process Engineering team in support of clinical patient testing in our high throughput CLIA lab. The PEA I is responsible for (1) developing new tools for improved clinical workflow efficiency, (2) working independently to troubleshoot instrumentation, and (3) identifying root causes of recurring errors with proper documentation to enable long term corrective actions. This role will enable an individual to gain both deep and broad experience in the areas of process engineering, data analysis, experimental design, and automation.  This position will also allow time to apply knowledge of coding languages like python and R to real world problems encountered within high paces and dynamic clinical laboratories.  This is considered an onsite role and will require the majority of days to be spent in the office.


  • Apply sound engineering practices to scale, optimize, and improve molecular biology methods.
  • Develop methods to compile and analyze large amounts of process data to assess for process stability, trending, and areas for improvement.
  • Develop and implement simple to medium complexity data and information handling tools to aid in efficient sample processing within the clinical laboratory. 
  • Apply six sigma, Design-for-quality, and 5S frameworks to existing or new processes to improve both capability, scalability, and quality of molecular diagnostic assays. 
  • Support high throughput CLIA lab through troubleshooting instrumentation and re-qualifying instrumentation back into clinical use
  • Identify root causes for process and instrument errors and develop short term and long term solutions. 
  • Develop effective training plans for clinical personnel on modified/improved workflows
  • Generate proper documentation for all troubleshooting and qualification


  • Bachelor’s degree or equivalent degree in biology or clinical related sciences
  • At least 6 months of experience with molecular biology techniques in a research or clinical laboratory
  • Excellent attention to detail
  • Effective written and verbal communication skills
  • Possess logical troubleshooting skills
  • Previous automation or clinical laboratory experience is preferred


  • Start-up experience
  • Knowledge of medical genetics
  • Experience in a cell-free DNA setting

Benefits And Perks:

  • Working with a team of ‘rockstars’ who bring out the best in everyone
  • Open, transparent culture that includes weekly Town Hall meetings
  • The ability to indirectly or directly change the lives of hundreds of thousand patients
  • Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered at 80%
  • Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
  • Retirement savings program including a 4% Company match
  • Free daily on-site lunches provided from top eateries
  • Latest and greatest hardware (laptop, lab equipment, facilities)
  • A variety of perks on campus (state of the art gym, restaurant)
  • Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based experience and salary/equity options split that the candidate chooses) (2) generous equity options offering, on top of (3) industry leading company benefits (free healthcare options, 401k match, very generous fully paid paternal leave etc.).

For this position, the base pay range is: $70,000-$80,000 per year.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

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