Be Biopharma is looking to hire a Associate Director, Immunology. We are looking for highly motivated, experienced, and innovative thinkers to join our growing team of passionate researchers to leverage B cells as a novel class of cellular medicine. This role will focus on developing allogeneic B cell medicines, designing strategies for in vitro and in vivo characterization of allogeneic prototypes, conducting, and overseeing experiments, and mentoring staff. It’s an exciting opportunity to make a difference in a novel therapeutic area that has transformative potential to impact patients’ lives.

Role & Responsibilities:

  • Design experimental strategies for the testing and validation of allogeneic B cell medicines in vitro and in vivo
  • Oversee characterization of immunological properties of allogeneic B cell prototypes
  • Guide establishment and troubleshooting of co-culture assays to profile allogeneic interactions of engineered B cells in vitro
  • Work hand-in-hand with Preclinical Pharmacology Team to devise in vivo validation plan, including selection and characterization of appropriate mouse models for the study of allogenetic cell products
  • Identify, establish, and optimize suitable readouts to thoroughly characterize interactions of engineered B cell medicines in vivo
  • Maintain awareness of latest developments in allogeneic cell therapy field and explore innovative approaches and techniques
  • Coordinate generation of comprehensive data package showcasing the performance of Be Bio’s allogeneic B cell medicines, and support regulatory filings
  • Training, supervision and development of staff

Minimum Experience, Education, and Specialized Knowledge and Skills:

Must thrive in a fast-paced, growing, and innovative environment where flexibility, resourcefulness, resiliency, and communication skills are key. Excellent interpersonal skills, ability to develop important relationships with your stakeholders, and being an all around good company citizen are essential.

  • PhD in Immunology or a related field
  • 5+ years of directly applicable experience in the pharma or biotech industry, or an academic group focused on the immunology of allogeneic cell therapies (title commensurate with experience)
  • Demonstrated record of scientific achievement (strong publication and/or patent record)
  • Deep immunology expertise is required, knowledge of B cell biology is preferred
  • Expert-level understanding of allogeneic shielding strategies
  • Deep expertise in conventional immunology techniques and cell-based assays
  • Proven ability to establish and troubleshoot co-culture in vitro assays (incl. MLR, NK-killing, and phagocytosis assays)
  • Expert knowledge of humanized and adoptive transfer mouse models for the study of allogeneic immunological responses
  • Strategic mindset, scientific creativity, ability to innovate, and aptitude for analytical problem solving
  • Enjoys managing and training staff, and fostering career development
  • Happily works collaboratively in a team with excellent communication and presentation skills
  • Enthusiastic and motivated with a positive can-do attitude

About Be Biopharma

Be Biopharma (“Be Bio”) is pioneering Engineered B Cell Medicines (BeCM) to dramatically improve patients’ lives who are living with cancer, rare diseases and other serious conditions. With eyes locked on the patient, our team of purpose-driven scientists, technologists, manufacturing experts and business builders collaborate to create a bold new class of cell therapies. Be Bio was founded in October 2020 by Longwood Fund and B cell engineering pioneers David Rawlings, M.D., and Richard James, Ph.D. from Seattle Children’s Research Institute. Be Bio is backed by ARCH Venture Partners, Atlas Venture, RA Capital Management, Alta Partners, Longwood Fund, Bristol Myers Squibb and Takeda Ventures. Since our founding, Be Bio’s investors have committed over $180 million to enable the Company to re-imagine medicine based on the power of B cell therapy. For more information, please visit us at Be.Bio and our LinkedIn page.

Culture

The beating heart of Be Bio is our People and together we are building a culture driven by purpose, passion, and that’s full of character.  We are “all-in” as we align ourselves with patients who need our medicines, and we embrace the highest standards of transparency, excellence, candor, collaboration, and team-based science with a shared ownership of company milestones and successes. 

Our commitment to our team members is to deliver a compelling, dynamic work experience that enables them to continually stretch, grow, and learn, that enriches their lives, that fosters a sense of belonging and community, and that goes above and beyond to support them in big, meaningful ways in both their personal and professional lives.  Be Bio is a team that works hard, plays hard, and supports each other on our shared journey to get transformative medicines to patients who need them. 

 

 

 

 

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