About Artizan Biosciences:

Artizan Biosciences is a growth-stage biotechnology company that utilizes a proprietary platform to identify critical microorganisms in our intestinal microbiota that play causative roles in important human diseases.  Using our technology, we define the specific mechanisms by which these organisms promote disease and then develop effective therapeutics to block these pathogenic processes. Through this approach, we are creating a portfolio of therapeutic agents that address important areas of unmet medical need in an unprecedented manner.  Artizan Biosciences was founded by leading Yale immunologists and is currently located at Science Park in New Haven, adjacent to the Yale University campus and within a growing biotech community. We are seeking additional talented scientists to join our team and help us deliver on the promise of our approach.
 
About the Position:

We are seeking a full-time Research Associate to support the characterization of microorganisms associated with human inflammatory diseases. This position entails working with a small and dedicated group of scientists in microbiology, immunology, and microbiome research in a dynamic team setting. The successful candidate will have relevant educational and practical experience and actively participate in the laboratory’s important research. In addition to versatility within the laboratory setting, this role requires a high level of self-motivation, responsibility, and ability to quickly gain new skills. The candidate must be capable of working independently as well as in a team environment.

Key Responsibilities

  • Perform DNA extraction, PCR, and high throughput DNA sequencing
  • Culture and isolation of pure bacterial species from complex community samples
  • Perform immunology, biochemistry, and molecular biology experiments with guidance
  • Perform immune phenotyping of various pre-clinical models of colitis and carcinogenesis using ELISA and multi-color flow cytometry
  • Develop and conduct in vitro assays using a variety of technologies and platforms
  • Conduct laboratory work and documentation according to SOPs
  • Maintain proper records and laboratory compliance in accordance with SOPs and safety policies
  • Troubleshoot and complete routine procedures independently and efficiently
Required Skills
  • High throughput nucleic acid sequencing and data analysis
  • Experience with immune and epithelial cell culture 
  • Experience developing, validating, and conducting in vitro assays 
  • Standard molecular biology procedures, including cloning, PCR, gel electrophoresis, and ELISA
  • Computational biology experience (command line, Python and/or PERL, R, Matlab)
  • Excellent research record-keeping practices
  • Flexibility to learn and adapt to new procedures
  • High motivation with a sense of urgency and responsibility
Minimum Qualifications:
  • Master’s degree, or bachelor’s degree with >5 years of experience, in biological sciences or related subject
  • Three years of biomedical research experience (preferably industry) in microbiology/molecular biology
  • Excellent organizational skills

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