About Arc Institute: 

The Arc Institute is a new scientific institution that conducts curiosity-driven basic science and technology development to understand and treat complex human diseases. Headquartered in Palo Alto, California, Arc is an independent research organization founded on the belief that many important research programs will be enabled by new institutional models. Arc operates in partnership with Stanford University, UCSF, and UC Berkeley.

While the prevailing university research model has yielded many tremendous successes, we believe in the importance of institutional experimentation as a way to make progress. These include:

  • Funding: Arc will fully fund Core Investigator’s (PI’s) research groups, liberating scientists from the typical constraints of project-based external grants.
  • Technology: Biomedical research has become increasingly dependent on complex tooling. Arc Technology Centers develop, optimize and deploy rapidly advancing experimental and computational technologies in collaboration with Core Investigators. 
  • Support: Arc aims to provide first-class support—operationally, financially and scientifically—that will enable scientists to pursue long-term high risk, high reward research that can meaningfully advance progress in disease cures, including neurodegeneration, cancer, and immune dysfunction.
  • Culture: We believe that culture matters enormously in science and that excellence is difficult to sustain. We aim to create a culture that is focused on scientific curiosity, a deep commitment to truth, broad ambition, and selfless collaboration.

Arc scaled to nearly 100 people in its first year. With $650M+ in committed funding and a state of the art new lab facility in Palo Alto, Arc will continue to grow quickly to several hundred in the coming years.

About the position:

Arc Institute is looking to hire a Vivarium Manager to join our Scientific Operations team. As the Vivarium Manager, you will oversee all core vivarium operational activities, develop vivarium SOPs, policies, and protocols and collaborate closely with scientists, lab operations professionals, and research support vendors and staff. 

In this position you will:

  • Manage and execute all core vivarium operational activities, train and supervise animal husbandry 3rd party support & and collaborate with Lab Operations on consumable ordering and inventory control.
  • Develop and oversee vivarium safety and operational protocols; effectively communicate and enforce safety rules; conduct orientation and annual safety and animal welfare training for all vivarium personnel and researchers..
  • Develop and maintain vivarium SOPs, policies, and guidelines in compliance with animal care and use protocol, IACUC, and Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC) guidance. Ensure vivarium readiness for IACUC and potential AAALAC inspections.
  • In collaboration with a reference person from each PI’s lab, edit, discuss, advise, and coordinate with the vivarium management and husbandry support vendor regarding animal projects and IACUC protocols. 
  • Supervise training and documentation for vivarium staff and serve as a technical resource for in vivo procedures like tail biopsy, pregnancy check, embryo collection, cardiac perfusion, organs and tissue collection, blood withdrawal, and oral gavage.
  • Add and train new users on the colony management software.
  • Manage controlled substance program, including ordering and distributing, training, compliance, and coordinating reverse distribution as needed, and collaborate with EH&S on obtaining licenses.
  • Manage upkeep, maintenance, calibration, and repair of vivarium equipment.
  • Execute ordering, shipping, and importation from domestic and international shipments of rodents, including the preparation of material for shipment and receiving from external vendors, collaborate on the policy for quarantining animals, and manage them.
  • Collaborate with labs on projects executed by vendors or outside institutions like rederivation and cryopreservation. 
  • Collaborate regularly with scientists and support staff to identify and address any workflow bottlenecks, inefficiencies, opportunities for process improvement, and logistical or administrative issues in the vivarium.
  • Maintain common supplies within the vivarium facility and coordinate with Facilities & Operations staff for waste removal.
  • In collaboration with Lab Operations, develop accurate estimations of staffing, operating expenses, and animal housing cost. Manage recharges to the lab for per diem and other associated costs. Participate in planning future CapEx/OpEx budgets for vivarium growth and development.

Requirements: 

  • 5+ years of experience in a laboratory animal facility, including 3+ years experience in a laboratory animal facility supervision or management role
  • Knowledge of regulations and national standards relating to the care and use of animals in research, issues pertaining to the care and use of animals in research, Institutional Animal Care and Use Committee (IACUC) responsibilities and procedures, and the role and value of animal use in biological research.
  • Strong organizational, communication, and interpersonal skills are required.
  • An understanding of accounting and budget preparation is preferred.
  • Experience in the management and tracking of rodent colonies
  • Hands-on experience in handling, dosing, blood sampling, and tissue harvest in rodents 
  • Strong attention to detail and ability to work independently with minimal guidance.

The base salary range for this position is $84,000 to $132,000. These amounts reflect the range of base salary that the Institute reasonably would expect to pay a new hire or internal candidate for this position. The actual base compensation paid to any individual for this position may vary depending on factors such as experience, market conditions, education/training, skill level, and whether the compensation is internally equitable, and does not include bonuses, commissions, differential pay, other forms of compensation, or benefits. This position is also eligible to receive an annual discretionary bonus, with the amount dependent on individual and institute performance factors.

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