Appia Bio is a preclinical stage biotech company founded in 2020 with the mission to bring innovative off-the-shelf cell therapies to cancer patients. Our novel platform can generate a broad array of allogeneic NKT and T cell types and can be engineered to address challenges in tumor microenvironments. Our goal is to discover and develop allogeneic cell therapies across a broad array of cancer indications with a scalability that increases access for patients.
Our research programs are rooted in leveraging T cell biology to generate NKT and T cell subtypes from hematopoietic stem cells. The scientific foundation of Appia Bio is underpinned by collaborative research led by Lili Yang (UCLA), David Baltimore (Caltech), and Pin Wang (USC), and further advised by a stellar scientific advisory board. The management team brings decades of experience in R&D, Technical Operations and business in the biotech industry.
About the Opportunity
Appia Bio is seeking a motivated Sr. Research Associate or Research Associate II to be part of the Process Design team with previous cell culture experience. The individual will be part of a team to enable the development of a groundbreaking allogeneic iNKT platform to treat cancer. They will be working in a highly collaborative environment to develop an innovative process for a manufacturable cell therapy product. This position will support the process design team in evaluating bioreactors and other scale-up technologies for manufacturing. The individual will be required to work independently and on a team in a fast-paced environment. Also, the individual should have good documentation practices and sterile lab techniques.
Ability to organize and collect data.
Experience culturing and passaging of adherent or suspension cells with aseptic techniques
Strict adherence to SOPs and cGMP regulations, the ability to accurately complete batch records.
Ability to function efficiently and independently in a changing environment
Execute experiments supporting optimization
Ability to think critically and demonstrated troubleshooting and problem-solving skills
Learn new technologies quickly and assist in optimizations.
Write and review technical documentation from writing technical SOPs, draft manufacturing batch records, technical reports, and summary reports.
MS in Biochemical/Chemical Engineering or Biology majors with 0-4 years of pharmaceutical manufacturing, technology transfer & process development experience OR
BS Degree in Biochemical/Chemical Engineering or Biology majors with 2-6 years of pharmaceutical manufacturing, technology transfer & process development experience
Comfortable working in a fast-paced environment with quick approaching deadlines
Excellent interpersonal, verbal, and written communication skills are essential in this collaborative work environment
Excellent skills in Microsoft excel, work, prism, and data analysis
Self-motivated, strong sense of responsibility, and willing to accept temporary responsibilities outside of initial job description
Ability to work in a cross-functional environment
Understanding of JMP and statistical analysis is a plus
Competitive Compensation Packages | Cost Sharing for Health Insurance Premiums | Flexible Work Environment | Untracked PTO | 401(k) Retirement Savings Plan Match | Life Insurance & Disability| Awesome Culture | Challenging & Fulfilling Work | Equity Options | and more
Appia Bio requires COVID-19 vaccination for all employees. As required by applicable law, we will consider requests for reasonable accommodations.
The statements herein are intended to describe the general nature and level of work being performed by employees assigned to this classification. They are not intended to be construed as an exhaustive list of all responsibilities, duties and skills required of personnel so classified.
Appia Bio is proud to be an equal opportunity workplace. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements.