About our Company
Appia Bio is a preclinical stage biotech company founded in 2020 with the mission to bring innovative off-the-shelf cell therapies to cancer patients. Our novel platform can generate a broad array of allogeneic NKT and T cell types and can be engineered to address challenges in tumor microenvironments. Our goal is to discover and develop allogeneic cell therapies across a broad array of cancer indications with a scalability that increases access for patients.
 
Our research programs are rooted in leveraging T cell biology to generate NKT and T cell subtypes from hematopoietic stem cells. The scientific foundation of Appia Bio is underpinned by collaborative research led by Lili Yang (UCLA), David Baltimore (Caltech), and Pin Wang (USC), and further advised by a stellar scientific advisory board. The management team brings decades of experience in R&D, Technical Operations and business in the biotech industry.

About the Role

Appia Bio is seeking an innovative Senior Scientist or Principal Scientist ready to take on the challenge and opportunity presented by the frontiers of creating novel cellular therapies. The immediate focus for this role will be to identify and validate cell therapy payloads/armoring techniques meant to boost the antitumor efficacy and persistence of iNKT-CAR cells, particularly against solid tumors. The Senior/Principal Scientist will join a culture of intellectual rigor and collegiality that has been built at Appia.

Responsibilities

  • Lead efforts to enhance Appia’s technology platform through the validation and integration of cell therapy payloads/armoring techniques
  • Contribute to the Biology research group with high scientific rigor, teamwork, and innovation
  • Develop strong cross-functional relationships and communicate effectively with peers, the executive staff, and other key stakeholders
  • Role may evolve to include pipeline project leadership and/or management responsibilities

Qualifications

The successful candidate will be an accomplished scientist with an established track record in academia and/or industry. The ideal candidate may have experience in T cell immunology, T cell development, immuno-oncology, or lentiviral vectors, with direct experience with CAR-T or other cell therapies as a plus. Hands-on experience with cell-based assays and complex flow cytometry panels is required.

  • A Ph.D. in Biology or a related field with a minimum of 6 years post-graduate research experience
  • Creative & rigorous problem-solving abilities
  • Track record of academic and/or industry excellence with clear evidence of success, including first author research publications in high caliber journals, conference talks, achievement of drug discovery milestones
  • Deep knowledge and keen intellect for integrating novel science and emerging technologies in the context of complex immunobiology
  • Highly motivated self-starter with strong presence, work ethic, and focus
  • Outstanding communication skills with the ability to build transparent and collaborative relationships across the company and with other stakeholders of the company
Benefits
Competitive Compensation Packages | Cost Sharing for Health Insurance Premiums | Flexible Work Environment | Untracked PTO | 401(k) Retirement Savings Plan Match | Life Insurance & Disability| Awesome Culture | Challenging & Fulfilling Work | Equity Options | and more
 
Appia Bio requires COVID-19 vaccination for all employees. As required by applicable law, we will consider requests for reasonable accommodations.
 
The statements herein are intended to describe the general nature and level of work being performed by employees assigned to this classification. They are not intended to be construed as an exhaustive list of all responsibilities, duties and skills required of personnel so classified.
 
Appia Bio is proud to be an equal opportunity workplace. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements.

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