Amylyx was started in 2013 by two Brown University students who had an ambitious goal: to improve the lives of people with neurodegenerative diseases by addressing the root cause. Their research and close collaboration with the ALS community ultimately resulted in our first commercial product, which is now approved in the U.S. and conditionally approved in Canada.

At Amylyx, we’re bringing together talented people like you who are guided by our values to be Audacious, Curious, Authentic, Engaging and Accountable in the fight against neurodegenerative diseases like, ALS, Alzheimer’s disease, Wolfram Syndrome and others.

Rediscover your purpose and reimagine your career at a company whose founders, mission, and culture are unlike any other in life sciences—in all the best ways.

Recent milestones include:

  • The U.S. Food and Drug Administration (FDA) approved RELYVRIO™ in September of 2022
  • Health Canada approved ALBRIOZA™ with conditions in Canada in June of 2022
  • AMX0035 is currently under review with the European Medicines Agency
  • 280 employees globally, with headquarters in Cambridge, MA, US and Amsterdam, the Netherlands -- and growing strong!


As a Lead IT Business Partner at Amylyx Pharmaceuticals, you will deliver and support IT-related initiatives and lead system implementations with accompanying components.  In this role you will directly interface with our commercial and communication teams including corporate communications, marketing, legal, commercial operations, field sales, and payer access.

To ensure Amylyx has a stable, robust, and scalable set of applications to support our growing business needs, it is imperative that our Lead IT Business Partner align cross functionally with other business partners.  This position will encompass many activities including: evaluating new functionality while maintaining the integrity of applications; partnering with other groups across the IT team, delivering on the business goals, refining existing solutions, and prioritizing the day-to-day of existing solutions. This critical role is highly visible and responsible for supporting multiple business groups.


  • Successfully implement and support Amylyx systems leveraging appropriate platforms.
  • Elicit, document, and execute on the overall systems strategy for business partners.
  • Oversee enhancements to all technology components used by supported groups within organization.
  • Support change management and governance activities by partnering with key business users to ensure new items are tested and implemented to meet the business needs.
  • Oversee test script creation, user testing and user documentation for systems.
  • Ensure appropriate IT processes, procedures, and standards are developed, monitored and are in place.
  • Introduce best practice and process improvement ideas where appropriate.
  • Occasionally manage projects using project management best practices.
  • Serve as the conduit between the customer community (internal and external customers) and the various services teams.
  • Elicit requirements using interviews and workshops, document analysis and business process descriptions, use cases, scenarios, business analysis, task, and workflow analysis.
  • Develop and foster effective relationships between the business, partners, and IT.
  • Manage external partners regarding applications and enhancements in line with the overall company objectives and solution capabilities.
  • Coordinate issue resolution with internal and external support providers.
  • Work with other IT team members to maintain roadmap for the integration of solutions with Veeva, Salesforce, and other SaaS solutions (e.g., data warehouse and analytical platforms).
  • Develop ad hoc reports using the tools available within the applications based on input from the business.
  • Lead small-group training sessions as needed.
  • Ability to learn new applications and functionality as additional needs arise.
  • Strong analytical skills with the ability to collect, organize, analyze, and disseminate significant amounts of information with attention to detail and accuracy.
  • Other duties as assigned.


  • Bachelor's degree in computer science or related field strongly preferred.
  • A minimum of 8 years of IT experience with progressively increasing technical and support responsibilities.
  • Minimum of 3 years of experience in working with, Veeva products, and/or other SaaS platforms.
  • Minimum of 3 years of experience supporting / working with a patient call center (or equivalent).
  • Experience supporting applications within the pharmaceutical/biotech industry (or equivalent).
  • Experience in interpreting the applicability of local and federal laws/regulations (including data privacy practices and laws) to company operations.
  • Demonstrated ability to manage several complex deliverables at the same time.
  • Excellent verbal and written communication skills and the ability to interact professionally with a diverse group of executives, managers, and subject matter experts.
  • Strong customer service orientation.
  • Ability to multitask – effectively manage work requests across multiple business areas.
  • Highly self-motivated and directed.
  • Ability to initiate, persuade, and influence others on the best solutions to action.
  • A strong drive to work on projects with minimum supervision while adding value to cross-functional teams and achieving goals.
  • Strong analytical skills required including a thorough understanding of how to interpret customer business needs and translate them into application and operational requirements.
  • Knowledge of FDA regulations, GDPR, SOX and/or HIPPA compliance is a plus.


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Amylyx is proud to be an Equal Employment Opportunity employer. We do not discriminate based upon race, religion, color, national origin, gender (including pregnancy, childbirth, or related medical matters), sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics. Accommodations are available for candidates who require them in our selection process. If you need an accommodation, please let your Amylyx Talent Acquisition contact know.

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