About Alltrna

Alltrna is the world’s first tRNA platform company to decipher tRNA biology and pioneer tRNA therapeutics to treat thousands of diseases. Alltrna unlocks tRNA biology to correct disease. The company's platform incorporates AI/ML tools to learn the tRNA language and deliver diverse programmable molecules with broad therapeutic potential. Alltrna has an unprecedented opportunity to advance a single tRNA medicine to unify treatment across a wide range of diseases with the same underlying genetic mutation. Alltrna was founded in 2018 by Flagship Pioneering. For more info, visit www.alltrna.com.

About The Role 

Come join a creative and collaborative team of scientists dedicated to leveraging emerging insights in RNA biology to develop novel classes of oligonucleotide therapeutics to treat human diseases and improve human health. In this role you will play a critical role in DMPK Group and work closely with internal partners and external collaborators to enable identification of multiple drug candidates for human clinical studies. Please apply if you feel that you can contribute to growing our team and advance our mission. As an early member of a privately held, well-funded, early-stage platform biotechnology company, you will contribute to the platform development, drug discovery, and translation into the clinic along with opportunities for professional growth. You will also benefit from opportunities to engage with the broader Flagship Pioneering ecosystem.

Core Responsibilities 

We are seeking a Nonclinical Studies Coordinator/Senior Coordinator to support a variety of the preclinical activities including bioanalytical, DMPK, and toxicology studies. The ideal candidate is a driven professional who knows how to contribute to multiple projects and activities in a nimble working environment and enjoys working in close collaboration with multiple functions in a small company environment. Principally, the position will interact with DMPK, Pharmacology, Discovery and other functions across the organization as well as external partners (e.g., CRO or academic organizations). This position will report to the Director, DMPK and is based in Cambridge, MA.

  • Manage and coordinate the scheduling of studies and technical resources with CRO partners; ensure timly coverage of internal needs.
  • Perform study monitor activities for nonclinical toxicology studies conducted at various CROs, working with the Study Director and the internal study lead.
  • Coordinate all aspects of outsourced nonclinical safety studies independently (e.g., assessing test material amounts requirements, determining availability, coordinating analytical testing and shipments/specimen shipment, protocol development, dose level selection presentations, on-site CRO monitoring, data and report review on an on-going basis, and study archival).
  • Support Nonclinical and Discovery efforts across multiple functions and capacities, including but not limited to compiling meeting minutes, tracking action items, executing logistics, managing documents and databases, coordinating timelines and milestones, and supporting team decision-making
  • Proactively identify risks, gaps, and resource bottlenecks while developing and implementing mitigation plans
  • Facilitate cross-functional communication by building strong working relationships across and between platform R&D, drug discovery & drug development

Qualifications and Skills

  • Qualified candidate should have at least a BS/MS and experience in the biotech/pharmaceutical industry.
  • Demonstrated ability to coordinate study execution at external organizations and ensure timely communication between all stakeholders
  • Experience in utilizing software tools for data management (sample inventory, tracking and chain of custody, document management, etc.)
  • Excellent verbal and written communication skills, interpersonal skills, strong organization skills and attention to details, ability to prioritize, and demonstrated ability to manage by influence and problem solve in a highly matrixed organization
  • Demonstrate the ability to work in a methodical and organized fashion; understand the material and documents workflow.
  • Basic experience working in a biochemistry -oriented wet lab is preferred, but not required.
  • Knowledge of general principles and methods of toxicology, animal welfare standards (USDA, AALAC, etc.), animal and human biology and physiology preferred
  • Be highly organized and able to work on multiple projects and meet established timelines.

What We’ll Offer You

  • Comprehensive, competitive healthcare and dental coverage through Blue Cross Blue Shield, vision coverage through VSP, family leave, paid time off, 401k retirement plan, disability and life insurance, and fully covered parking/commuter benefits.
  • A dynamic early-stage work environment and highly interdisciplinary, talented, and collaborative team.
  • Participation in an unprecedented opportunity to advance a single tRNA medicine to restore disrupted protein production, regardless of target, for thousands of diseases with the same underlying genetic mutation.
  • Professional growth opportunities through mentoring, training, immersion in cross-functional projects, and opportunities to learn and try new things.
  • Daily on-site snacks, cold brew coffee, and Bevi, as well as weekly catered lunches.

Our Core Values

Fast-acting/efficient. Moves quickly and proactively with a strong work ethic to produce high-quality results while fostering a positive work environment. Focuses on key priorities. Demonstrates tenacity and willingness to go the distance to get something done.

Integrity. Does not cut corners ethically. Earns trust and maintains confidences. Does what is right not just what is politically expedient. Speaks plainly and truthfully. Follows-through on commitments. Expects a high level of personal performance and team performance.

Critical thinking. Learns quickly. Demonstrates ability to proficiently understand new information and independently achieve meaningful outcomes. Able to structure and process qualitative/quantitative data and draw insightful conclusions.

Creativity & Innovation. Generates new and creative approaches to problem solving. Positive ‘can-do’ attitude. Views the toughest challenges as the greatest opportunities for personal growth and company innovation.

Teamwork. Fully engaged in facilitating personal and team success. Reaches out to peers and cooperates with the team to establish an overall collaborative work environment. Often solicits and responds well to constructive feedback. Possesses good written and oral communication skills with the ability to clearly and concisely convey ideas and opinions.

Flexibility/adaptability. Adjusts quickly to changing strategic and tactical priorities. ‘Wears multiple hats’ and is comfortable with ambiguity.

Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

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