Company Overview

At Aditum Bio, our mission is to give patients access to medicines that may not otherwise be developed. Co-founded by industry veterans Joe Jimenez, former CEO of Novartis and Mark Fishman, former President of the Novartis Institutes for Biomedical Research, the firm in-licenses promising therapies that for some reason are not advancing toward the clinic.  The firm focuses on the translational phase of medicine to generate data that can support full clinical development, and eventual market launch, to reach patients in need.

Position Summary

The Sr Director, Nonclinical Pharmacology/Translational Biology will be responsible for the design, execution, and interpretation of nonclinical in vitro/in vivo pharmacology studies to support Aditum Bio’s drug development programs. In addition, this individual may be called upon to help build clinic-ready exploratory biomarker and PD assays. The Sr Director, Nonclinical Pharmacology/Translational Biology will work collaboratively with cross-functional teams to advance our therapeutic candidates from preclinical stages toward clinical development on the shortest timelines possible while mitigating risks and minimizing spending.

Position Responsibilities:

  • Set nonclinical pharmacology strategy for Aditum Bio affiliates
  • Vet and oversee relevant vendors, partners, and consultants to enable execution of necessary mechanistic and IND-enabling nonclinical studies as well as PD and exploratory assay development
  • Critically analyze data generated to inform scientific program strategy, program decisions and subsequent stages of drug development
  • Ensure the integration of nonclinical findings with planned clinical programs and when necessary, partner with Translational Medicine and Clin Ops to support clinical assay development
  • Work collaboratively program team leads and other team members and stakeholders across Aditum Bio affiliates to maintain timelines, budget and deliverables
  • Secure cross functional alignment during discussion of opportunities, risks, and mitigations
  • Execute plans and provide reports in accordance with regulatory guidelines and expectations; contribute to drafting IND and other regulatory documents
  • Contribute to due diligence and gap analysis on potential Aditum Bio assets

Qualifications:

  • PhD in Pharmacology, Cell Biology, or similar life sciences-related field
  • At least 10 years in pharmacology and/or translational research role (pharmaceutical company or biotech), developing small and large molecules for various indications
  • Experience building and managing collaborations with CROs, consultants, pharmaceutical partners and external organizations
  • Experience designing, executing, and managing in vivo and in vitro studies with strong data analysis skills and proficiency presenting data
  • Strong problem-solving skills, ability to efficiently identify and resolve critical issues
  • Independent contributor with excellent collaboration skills, an ability to communicate effectively with a variety of stakeholders both internal and external, flexible and skilled at juggling multiple projects across different indications
  • Strong leadership skills with the ability to be hands-on as well as lead/manage pharmacology programs
  • Desire to build a broad understanding of drug development across a number of non-oncology indications

The range for this full-time position is $230,000 - $260,000, plus a target bonus, equity compensation and benefits including medical, dental, vision, and 401k. Our salary ranges are determined by role, level and location. The range displayed on our postings reflects the minimum and maximum for new hire salaries. Within the range, individual pay is determined by interview performance, job-related skills, experience and relevant education and training. Please note the range reflects base salary and does not include target bonus, equity or benefits.

 

We provide equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.

 

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