At 2seventy, it’s all about time – how you use your time to do meaningful work that matters, who you choose to spend your time with, and how we can give more time to our patients. When you join us, you are so much more than a number – we invite you to bring all of you and become part of a community where we believe we are better 2gether. Are you ready to re-think the (im)possible? Not only are we ready – we are doing it. The time is NOW.
How you’ll make an impact:
Our Seattle site is currently seeking a Senior Associate Scientist within the Research and Technology Development group to support pre-clinical efforts in the early product development space of CAR and TCR T cell therapies. This lab-based role will enable the candidate to contribute to an early discovery research team working closely with our scientists to drive innovative new cell therapy projects forward. The ideal candidate is passionate about addressing the critical unmet medical needs of patients; displays a high level of curiosity and creative problem-solving; and is keen to work within cross-functional teams.
About the team:
The Research and Technology Development team is passionate about developing best-in-class T cell therapies that deliver new hope for patients with cancer. Whether we are transforming the field of immuno-oncology, or finding new ways to iterate and improve, we are driven by a personal commitment to changing the lives of our patients. We are focused on fully realizing the potential of unlocking the complexities of tumors and the hostile microenvironment that they create.
How you’ll spend your time:
As a Senior Research Associate, you'll help to bring more patients more time by:
- Designing and Cloning CAR/TCR constructs into lentiviral vectors
- Engineering T cells with CARs or TCRs using lentiviral vectors
- Culturing and characterizing tumor cell lines, including engineering of gene overexpressing and knockout cell lines
- Performing in vitro immunological assays including but not limited to flow cytometry, ELISA/MSD, cytotoxicity analysis
- Collaborating with cross-functional and cross-site teams to plan experiments and obtain test materials and reagents
- Contributing to study design, execution, and data analysis
- Compiling and presenting data
- Maintaining detailed and accurate documentation in an electronic lab notebook
Who you are and what you’ve accomplished:
- BS/MS in cell biology, immunology, oncology, or related discipline with 5+ years’ experience
- Extensive experience in molecular biology techniques, including construct design, cloning, cell line engineering, lentivirus production, WES/western blot and qPCR
- Experience with mammalian cell culture, such as tumor cell lines – primary T cell experience is a plus
- Experience with flow cytometry and FACS
- Experience with standard immunological assays such as MSD/Luminex/ELISA is a plus
- Working knowledge of various software (e.g. Microsoft Office, FlowJo, GraphPad Prism, FACSDiva, Geneious)
- Ability to effectively plan and organize work activities to meet schedules and deadlines
- Effectively work independently and as part of a collaborative team comprised of multiple functional groups
We offer a total compensation and rewards package that ranks among the best in our industry. Base pay is one part of our total compensation package and is determined within a range. This provides the opportunity to progress as you grow and develop within a role. The anticipated annualized salary range for this role is $95,000 - $110,000 (Senior Associate Scientist I) and $105,000 - $120,000 (Senior Associate Scientist II). Your base pay will be determined based on several factors including demonstrated skills, relevant education or training, experience, qualifications, travel requirements, and job location. Our overall package also includes stock, bonuses, and benefit programs which include health, dental, vision, life insurance, 401(k), lifestyle benefits, parental leave, a flexible time off program, as well as 27 paid holidays including 2 company shutdowns. You can learn more detailed information about our suite of benefits here
